Presence of a preservative in an ocular medication has often been considered a culprit in damaging the epithelium. However, the inclusion of a preservative is equally necessary, especially in multiple-dose containers, in order to protect against dangerous organisms accidentally gaining access during instillation. Benzalkonium chloride (BAK), chlorobutanol, chlorhexidine acetate (CHA), and pheny...

Isotonic, neutral buffered solutions of benzalkonium chloride or chlorhexidine digluconate were applied topically to one eye of rabbits or human subjects. Contralateral control eyes received phosphate buffered saline as placebo. One-half hour later, the tear film of both eyes was loaded with nonpreserved sodium fluorescein. Anterior chamber fluorescence levels were measured at 1 hr intervals to...

Various aqueous and oily diclofenac ophthalmic formulations were subjected to accelerated and long term stability studies. Degradation of diclofenac was found to follow first-order kinetics. Among the aqueous formulations containing preservative, formulation with PMA, PMN, SA, MP/PP and SMS showed diclofenac content above 90% after 6 months of accelerated and 12 months of room temperature stora...

This review discusses the status, antimicrobial mechanisms, application, and regulation of natural preservatives in livestock food systems. Conventional preservatives are synthetic chemical substances including nitrates/nitrites, sulfites, sodium benzoate, propyl gallate, and potassium sorbate. The use of artificial preservatives is being reconsidered because of concerns relating to headache, a...

This research was conducted to determine the percentage of moringa leaf extract inhibit deterioration quality tilapia fillet as a natural preservative against organoleptic characteristics during room temperature storage. carried out at Processing Fishery Products Laboratory, Aquaculture Laboratory Faculty Fisheries and Marine Sciences, Central Padjadjaran University, Jatinangor. The method used...

Background & Aim:Nowadays, the use of chemical preservatives has been limited due to the controversial adverse effects. In this study, we evaluated the preservative potency of product with active herbal ingredients (Barij Baby cream) in contrast with the same products with two different chemical preservatives including methylparaben plus propylparaben and potassium sorbate plus...

Wood preservative treatments are indispensable for wood used in severe environmental conditions. Decay occurs in preservative-treated woods due to the poor impregnation of sapwood; this problem has recently gained attention for Cryptomeria japonica kiln-dried logs. To clarify the causes of this phenomenon, the influence of drying temperature on the penetration of preservative into sapwood logs ...

None of the commercial HPV tests are U.S. FDA-approved for testing of cervical cytology specimens in SurePath preservative. Still, ~30% of HPV testing is performed on specimens in this formalin-containing preservative. Formalin-induced DNA fragmentation and cross-linking may interfere with HPV detection. We evaluated analytical sensitivity and specimen stability of the cobas 4800 HPV (Roche) an...

Gerbera(Gerbera jamesonii) from the family of Asteraceae is regarded as one of the best cut flowers in the world. Despite of the publicity of Gerbera’s cut flowers, they have a short postharvest life. The objective of the present study was to study the replacement feasibility and the comparison of thymol (isolated from zataria), and essential oils of peppermint and rosemary (200, 400 and 600 mg...