The present study was under taken to assess the comparative e f fec t s o f neb ivo lo l wi th p roprano lo l and a teno lo l on psychomotor performances. Thirty healthy volunteers were randomized into three groups with n=10 in each group. Each subject received single dose of one of the three medications (nebivolol 5 mg, atenolol 50 mg and propranolol 40 mg) in morning (9.00 AM). Just before ad...

Non-enzymatic browning (NEB) development was studied in dehydrated potato at 70°C. It was related to the macroscopic and molecular properties and to water-solid interactions over a wide range of water activities. Time resolved (1)H NMR, thermal transitions and water sorption isotherms were evaluated. Although non-enzymatic browning could be detected in the glassy state; colour development was h...

In this work we present the atomistic computational study of adsorption properties Co doped MoS2 adsorbed ammonia (NH3) and methane (CH4). The distance, energy (Ead), charge transfer (Qt), bandgap, Density States (DOS), Projected (PDOS), transport properties, sensitivity recovery time have been reported. diffusion property system was calculated using Nudge Elastic Band (NEB) method. results dep...

Fifty Holstein cattle, either second to fourth generation daughters of cows randomly bred to non-commercial sires originating in the Virginia Tech dairy herd (estimated mean PDM84 = -455 kg, control animals), or daughters of cows bred to commercially available sires (mean PDM84 = +368 kg, selection animals), were randomly assigned to be milked twice or thrice daily starting at parturition. Seri...

A new sensitive, simple, rapid, accurate and precise method for simultaneous quantification of nebivolol HCl (NEB) and hydrochlorothiazide (HCT) in combined tablet dosage form has been developed. The method is based on the derivative spectrophotometric method at zero-crossing wavelengths. Two wavelengths 280nm (zero crossing point for NEB) and 272.2nm (zero crossing point for HCT) were selected...

Reduced oocyte and embryo quality are currently recognized as key factors in the problem of disappointing fertility in high producing dairy cows, but also in women undergoing assisted reproductive treatment. This review aims to highlight the importance of intrafollicular conditions in the subfertility problem, topical in both bovine and human research. Metabolic disturbances, like a negative en...

The epithelium of intrapulmonary airways in many species harbors diffusely spread innervated groups of neuroendocrine cells, called neuroepithelial bodies (NEBs). Data on the location, morphology, and chemical coding of NEBs in mammalian lungs are abundant, but none of the proposed functions has so far been fully established. Besides C-fiber afferents, slowly adapting stretch receptors, and rap...

Does the nebulin ruler hypothesis stand up to experimental tests? Nebulin’s possible role as a ruler has been tested in several ways, and thus far the results appear to argue against its controlling thin filament length. Two such pieces of evidence are: first, the nebulin molecule appears to be somewhat shorter than the thin filament in most fibre types; and second, in nebulin gene knockout mod...

A recent study has shown that the giant protein nebulin maintains the lengths of actin filaments in striated muscle cells. Although on the surface, nebulin looks like a molecular ruler, it may be playing a more complex role in regulating dynamics at the pointed end of actin filaments in striated muscle.

Studies on the correlation between expression and/or autolysis of calpain and postmortem proteolysis in muscle have provided conflicting evidence regarding the possible role of calpain 3 in postmortem tenderization of meat. Thus, the objective of this research was to test the effect of postmortem storage on proteolysis and structural changes in muscle from normal and calpain 3 knockout mice. Kn...