a r t i c l e i n f o

A synthesis of functionalized fused pyrimidine derivatives from the respective ortho-nitroaromatic carboximes is described. Commercially available nitroarenes were transformed according to a known manner into the ortho-nitroaromatic carboximes. Selective catalytic reduction of the nitro group in these compounds followed by condensation of the amines formed with various orthoesters, resulted in ...

Timing is one of the most critical factors of software size estimation. We need to know quite a bit about the software project to make a meaningful size estimate. However, most of the software estimates should be performed at the beginning of the life cycle, when we do not yet know the problem we are going to solve. In the literature, there are few early size estimation methods. This study demo...

Interaction between nitrobenzene and silver cluster is investigated using the Density Functional Theory (DFT) at the B3PW91 level of theory. Adsorption causes a variation in the structural parameters. The charge transfer from silver cluster to nitrobenzene is identified from the plot of the molecular electrostatic potential (MEP) surface and natural population analysis (NPA). A marked enhanceme...

The following questions are discussed: " Why confidence intervals are a hot topic? " ; " Are confidence intervals objective? " ; " What is the usefulness of coverage? " ; " How to obtain useful information from experiment? " ; " The confidence level must be chosen independently from the knowledge of the data? " .

Os efeitos da variação da concentração da amostra nos valores de deslocamento químico e nas velocidades de relaxação spin-rede seletiva (R1 ) e não seletiva (R1 ) foram medidos em solução para os três isômeros das guanil hidrazonas derivadas do nitrobenzaldeído (NBGH) puros e com a albumina do soro bovino (BSA). Os resultados foram usados para determinar o tempo de correlação (τc), mostrando qu...

We study the quark confining vacuum structure, with the objective to liberate quarks and gluons at high temperature. The present day experimental effort involves colliding heavy nuclei and this limits the domain of deconfinement to the size of the atomic nucleus. The ‘free’ quarks and gluons form a thermal gas comprising color charges, the quark–gluon plasma — a hot soup of elementary matter, l...

Background Approximately 5–15% of patients with juvenile idiopathic arthritis belong to a subcategory of enthesitis related arthritis (ERA), which is strongly associated with HLA-B27 and male gender. Recent investigations have suggested markedly low discontinuation rates of antitumour necrosis factor (anti-TNF) agents in those with ERA, in whom reports on long-term efficacy and safety of anti-T...

Points of view or opinions in this document are those of the author and do not necessarily represent the official position or policies of the U.S. Department of Justice. INTRODUCTION The for-profit bail bonding industry has relied upon several recent studies to make the claim that commercial surety bonds are the most effective type of pretrial release. This paper provides an overview of those s...

When moving through cluttered environments we use different forms of the same source of information to avoid stationary and moving objects. A stationary obstacle can be avoided by looking at it, registering the differential parallactic displacements on the retina around it during pursuit fixation, and then acting on that information. Such information also specifies one's general heading. A movi...