Seroprevalence of Ig G and M Antibodies in Individuals with Herpes Simplex Virus -1 &2 Infection HIV Positive Negative South Indian PopulationSubha Priya Venkateshwaran, Kamaraj Murugesan, Rajeshwari Sivaraj

Seven neonates with proven herpes (HSV type 2) encephalitis exhibited a characteristic sequence of findings on cranial computed tomography (CT). The initial CT abnormalities in all infants were fingerlike areas of cortical increased attenuation noted on unenhanced scans obtained 2-30 days after presentation. These usually were accentuated by increased white-matter lucency. Subsequently (more th...

Ocular infections with herpes simplex virus 1 can lead to corneal scarring and blindness, with herpes keratitis being the major infectious cause of blindness. There is currently no clinically approved vaccine and nearly all developmental vaccines are targeted against HSV-2 and genital herpes. We tested the ability of an HSV-2 replication-defective virus, a genital herpes vaccine candidate, to p...

In this issue of the Journal, Tata and co-workers present data from a small, intensively studied group of women with genital herpes due to herpes simplex virus (HSV) type 2, demonstrating that during a 30-day period these women experienced both symptomatic and asymptomatic genital viral shedding bilaterally and at areas innervated by dorsal root nerve ganglia on both sides of the midline [1]. T...

INTRODUCTION The changing epidemiology of genital herpes in Edinburgh is described in relation to herpes simplex virus (HSV) Type 1 and herpes simplex virus Type 2 infection over a period of 14 years. METHODS 2018 episodes of genital herpes in 1794 patients over a 14 year period were assessed. Data on age, sex, sexual orientation, geographical origin and herpes antibodies were also analysed. ...