The progressive growth of neoplasms and the production of metastasis depend on the development of adequate vasculature, i.e., angiogenesis. The extent of angiogenesis is determined by the balance between positive- and negative-regulating molecules that are released by tumor and host cells in the microenvironment. The growth of many neoplasms is associated with the absence of the endogenous inhi...

sis, an outstanding characteristic of neoplastic cells, remains unexplained. This phenomenon has been variously attributed to disturbances of res piration, to deficiencies of electron transport en zymes or co-factors, and to a lack of the citric acid cycle (2, 4, 14, 23). However, none of these hy potheses has decisive experimental support, and against them can be cited the observations that tu...

specifically. The book is supported by over 200 references and half again as many personal communications. The high-quality scanning electron micrographs of pollen grains are especially appealing. Willow, mimosa, and dandelion pollen have an architecture as intricate and beautiful as the plant superstructure which supports them. The spiny spherical pollen grains of ambrosia (ragweed) make them ...

Paneth cells were discovered by Schwalbe in 1872 and described more fully by Paneth in 1888. They have been found since in the intestinal mucosa of a wide variety of animals. They are found in the fundus of the crypts of Lieberkuhn and their characteristic feature is the large granules visible in both the fresh and fixed state in the apical or upper part of the cell (Fig. 1). In man they occur ...

AIM We designed this study to investigate the neutrophil lymphocyte ratio as a biomarker in distinguishing colonic polyps which are neoplastic or non-neoplastic. MATERIALS AND METHODS One hundred and twenty-five patients with colonic polyps were enrolled into the study. The following data were obtained from a computerized patient registry database: mean platelet volume (MPV), uric acid (UA), ...

Localized gingival growths are one of the maximum regularly encountered lesions within oral cavity, which taken into consideration to be reactive as opposed neoplastic. Those encompass pyogenic granuloma, inflammation fibroma, peripheral large cellular and ossifying fibroma (POF). Among those lesions, Peripheral Ossifying Fibroma (POF) is an occasionally happening non-neoplastic growth with reg...

Abnormalities in iron metabolism are frequent in the neoplastic disease. The relationship between hepcidin and iron homeostasis in cancerous pathology is incompletely known, although it has been studied during the last years. This paper aims to analyze the role of hepcidin in the neoplastic processes, its correlation with carcinogenesis and anemia, and with the disease activity. It must be ment...