Carcinoid tumour is a rare entity accounting for less than two percent of bronchial neoplasms. They are rare welldifferentiated, neuro-endocrine tumors, with low-grade malignancy. They are distinguished in two different groups: typical and atypical carcinoid. Typical and atypical carcinoids differ in their biological behavior and prognosis. Atypical bronchial carcinoid tumor is still rare. We r...

Francisca Lago1, Rodolfo Gómez2, Javier Conde2, Morena Scotece2, Carlos Dieguez3 and Oreste Gualillo2 1SERGAS Santiago University Clinical Hospital, Research Laboratory 7 (Molecular and Cellular Cardiology), Santiago de Compostela, 2SERGAS Santiago University Clinical Hospital, Research Laboratory 9 (NEIRID LAB, Laboratory of Neuro Endocrine Interactions in Rheumatology and Inflammatory Disease...

Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominantly inherited disorder, characterised by the occurrence of tumours of the parathyroid glands, the pancreatic islets, the pituitary gland, the adrenal glands and neuroendocrine carcinoid tumours. Carcinoid tumours of the thymus and pancreatic-duodenal gastrinomas are the most harmful tumour types, since these tumours have malignan...

BACKGROUND Several studies have evaluated the clinical effectiveness of endocrine therapy alone in women aged 70 years or over and who are fit for surgery. OBJECTIVES To identify and review the evidence from randomised trials comparing primary endocrine therapy (endocrine therapy alone) to surgery, with or without adjuvant endocrine therapy, in the management of women aged 70 years or over wi...

Phenytoin (Diphenyl Hydantoin or Dilantin) is highly effective and widely prescribed anticonvulsant agent used in the treatment of grand mal and psychomotor epilepsy. Phenytoin has been used to treat thought, mood and Behavior disorders, cardiovascular disorders, Neuro muscular disorders, gastrointestinal disorders, Endocrine disorders.

Various prostaglandins (PGs) have been found in several areas of the brain. PGs of the E series have been found in the pituitary and pineal glands and the median eminence, and they have been shown to influence hypothalamic endocrine-release characteristics and release of melatonin from the pineal gland. It has been suggested that they may act, along with membrane phospholipids, as a link betwee...

Long-term endocrine disorders are the most frequent complications in survivors of adult and paediatric nasopharyngeal carcinoma (NPC). The hypothalamic-pituitary (h-p) axis lies within the field of radiation therapy for NPC. Consequently, neuro-endocrine abnormalities due to radiation-induced damage of the h-p occur in the majority of patients followed long term. Similarly, radiation injury to ...

Previously, we demonstrated acupuncture at acupoint HT7 (Shen-Men) attenuated ethanol withdrawal syndrome by normalizing the dopamine release in nucleus accumbens shell. In the present study, we investigated the effect of acupuncture on anxiety-like behavior in rats and its relevant mechanism by studying neuro-endocrine parameters during ethanol withdrawal. Rats were treated with 3 g kg(-1)day(...

BACKGROUND Somatostatin receptor scintigraphy (SRS) and octreotide therapy have both changed the management of gastroenteropancreatic endocrine tumours, but very few data are available on the use of SRS and octreotide to visualise and treat somatostatinomas. METHOD The results of SRS and octreotide treatment in three somatostatinoma patients were examined. RESULTS SRS was able to detect ext...

Neuroendocrine tumours (NETs) are a diverse, highly heterogeneous group of neoplasms derived from endocrine cells found in the neural crest. NETs typically display endocrine metabolism and slow growth, while displaying a wide range of presentations and clinical symptoms. Demonstrating typically small lesions, with varying anatomical localisation, diagnosis is typically in the advanced stages of...