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Pain is a pivotal symptom faced by patients with rheumatic disease. Nevertheless, mechanisms of articular pain remain unclear and there is little correlation between pain, disability, and radiological change. ' Although a protective function for the pain sensory system has long been assumed, Wall and others have suggested that the system may also function to modify local responses to tissue tra...

William Meggs's recent article, "Neuro-genic Inflammation and Sensitivity to Environmental chemicals" (EHP 101:234-238), provides a useful introduction to a rapidly growing area of knowledge in physiology and posits a number of interesting hypotheses regarding the health effects of airborne chemicals. Some specific technical points, however, merit comment. Meggs describes the common chemical se...

Biomimetic Periosteum In article 2203027 by Yanlin Su, Kaifang Chen, Daping Quan, Xiaodong Guo, and co-workers, [email protected] electroactive biomimetic periosteum is created, which can regulate the concentration of axon initial segments in sensory nerves, promote bone regeneration releasing neuropeptides. This will enrich theory neurogenic provide a promising treatment for defects.

one-hundred and sixteen children with esrd were registered in shiraz pediatric hemodialysis center in nemazee hospital, a referral center in the south of iran, from 1990 to 1999. very small children are not dialysed in this center due to technical problems. the age range of children in this center was 2-16 years, mean age was 10.4±3.6 years and male to female ratio was 1.4. major causes of esrd...