1. Sugarman JL. Epidermal nevus syndromes. Semin Cutan Med Surg. 2007;26:221-30. 2. Solomon LM, Fretzin DF, Dewald RL. The epidermal nevus syndrome. Arch Dermatol. 1968;97:273-85. 3. Solomon LM, Esterly NB. Epidermal and other congenital organoid nevi. Curr Provi Pediatr. 1975;6:1-56. 4. Singal A, Dhaliwal U, Bhattacharyya SN , Rohatgi J, Singh N. Complex ocular choristomas in linear nevus seba...

The authors report a rare case of primary orbital melanoma (POM) combined with giant divided nevus of the eyelid. An 8-year-old Chinese girl is referred for evaluation of 2-month duration of exophthalmos with decreased vision, epiphora, and pain on her right eye. His presentation, imaging, biopsy, histopathology, and management are presented. The possible cellular origin of the POM and the rela...

Divided nevus, also known as kissing nevus, is a rare variant of congenital melanocytic nevi in which there are two adjacent nevi in areas of the body that undergo embryonic cleavage. The original description of this type of lesion was on the eyelid. The location on the penis is even rarer, with only 17 case reports in the literature so far, and only one of them described the dermoscopic findin...

to malignant melanoma. The exact cause is unknown. There may be hereditary factors, autosomal dominance or other multifactor determinants. Management depends upon size, location and malignant transformation. Surgical excision is the mainstay of treatment. Cultured epidermal autograph has been used successfully to cover postoperative large surface area defect. We report a one-day-old male child ...

Papillomatous Compound Nevus An 8-year-old boy was observed for 5 years for an enlarging, pigmented lesion on his left lower lid (Fig 1). An excisional biopsy was performed and histopathology (H&E) revealed skin with keratinized, stratified squamous epithelium in a papillomatous configuration (Figs 2 and 3). The lesion had nests of densely pigmented melanocytes within the epithelium (black arro...

Differentiation of a melanocytic nevus and melanoma is often a dilemma clinically as well as histologically. This dilemma involves inexperienced as well as knowledgeable pathologists. The provoking question turns out to be: why is this differential diagnosis often a quandary? The answer lies in the fact that there are overlapping cytological and architectural criteria used interchangeably for a...

We report phakomatosis pigmentovascularis (PPV) detected in a 40- year-old male characterized by the presence of a port-wine stain in the background of aberrant Mongolian spots covering the back, nevus of Ota, ocular melanosis, epidermal nevus and a scaly patch with the diagnosis of discoid lupus erytematosus. These associations have not been reported yet.

neous biopsies, yielding 69 collision tumors. Cascajo and colleagues found 54 collision tumors of malignant cutaneous neoplasms associated with seborrheic keratoses in 85,000 biopsies. The most common combinations found by Boyd and Rapini included basal cell carcinoma and nevus (14), basal cell carcinoma and seborrheic keratosis (8), nevus and seborrheic keratosis (14), actinic keratosis and ne...

OBJECTIVE To determine the frequency of and the histologic and clinical factors associated with melanoma existing in histologic contiguity with a nevus. DESIGN Pathology reports from melanomas collected from January 1, 1993, to December 31, 1997, were retrospectively reviewed. SETTING Independent, community-based dermatopathology laboratory. PATIENTS A total of 1606 patients with a histol...