Vitiligo, an autoimmune disorder, is known to co-localize with other immunological disorders like lichen planus and psoriasis. However, there are no reports regarding the co-localization of an autoimmune disorder (vitiligo) and a developmental disorder (verrucous epidermal nevus). We hereby present a 10-month-old infant who was visited for white patches on the right buttock and adjoining antero...

When dermatologists see acquired and wellcircumscribed pigmented macules on the palm, dorsal hand or forearm of the elderly, they tend to consider blue nevus, hematoma, nevus cell nevus and malignant melanoma as differential diagnoses [1]. We herein described the very rare case of localized lentigo accompanied by post-inflammatory pigmentation in a patient who has been treated for palmoplanter ...

Malignant melanoma (MM) is a type of malignant tumor, which originates from neural crest melanocytes. MM progresses rapidly and results in a high mortality rate. The present study aims to investigate the expression of microphthalmia transcription factor (MITF), the S100 protein, and HMB-45 in MM and pigmented nevi. A total of 32 MM samples (including three skin metastasis, three lymph node meta...

Nevus spilus is the term usually given to a pigmented skin lesion, congenital or acquired, that may occur anywhere on the body, consisting of a large light tan patch with numerous superimposed darker scattered maculae or papulae that are flat or slightly raised. For a long time, nevus spilus was believed to be a benign lesion. However, in 1957 Perkinson reported a melanoma appearing on nevus sp...

pseudoinclusions are sometimes evident and mild nuclear pleomorphism is typical. Mitoses are either absent or extremely infrequent. By definition dendritic cells are said not to be seen in this lesion. The growth pattern often presents a plexiform appearance, fascicles of nevus cells following the dermal appendages and neurovascular bundles. Perineural or endoneural extension is a very common f...

Ota's nevus is mongolian spot-like macular blue-black or gray-brown patchy pigmentation that most commonly occurs in areas innervated by the first and second division of the trigeminal nerve. Acquired, bilateral nevus of Ota-like macules (ABNOM) is located bilaterally on the face, appears later in life, is blue-brown or slate-gray in color. It is not accompanied by macules on the ocular and muc...

Giant congenital melanocytic nevi are rare and occur in about one out of every 2,00,000 to 5,00,000 births. There is a significant association between bathing trunk nevus and neurofibromatosis and lipomatosis. Apart from this, association of bathing trunk nevus with abnormalities like spina bifida occulta, meningocele, club foot and hypertrophy or atrophy of deeper structures of a limb, have be...

Epidermal nevus syndrome (ENS) is a rare condition characterized by congenital epidermal nevi (EN) associated abnormalities of other organs including central nervous system (CNS), skeletal system, eyes, and oral cavity (1). ENS is divided into a group of distinct disorders, based on the associated epidermal nevus and genetic inheritance pattern. Organoid nevus could be seen in some ENS, includi...

Actas Dermosifiliogr. 2009;100:329-43 333 To the Editor: There are several types of dermatosis that may occur around the melanocytic nevi, although there are few reported cases of each of these. The most representative of these dermatoses is halo nevus1 (Sutton nevus, leucoderma acquisitum centrifugum), but there are other named examples including Meyerson nevus2 (halo dermatitis), targetoid ne...

Vellus hair follicle Accessory auricle Trichofolliculoma Hair nevus Abstract We present a case of hair follicle nevus, a rare hamartoma composed of vellus hair follicles. Hair follicle nevus should be differentiated from accessory auricle, trichofolliculoma and hair nevus. Masahiro Tani, MD, Department of Dermatology, Kobe University School of Medicine, 5 Kusunoki-cho, 7 chome, Chuo-ku, Kobe 65...