Transforming growth factor beta1 (TGF-beta1) has been previously shown to modulate interleukin 2 (IL-2) secretion by activated T-cells. In the present studies, we determined that TGF-beta1 induced IL-2 mRNA expression in the murine T-cell line EL4, in the absence of other stimuli. IL-2 mRNA expression was significantly induced by TGF-beta1 (0.1-1 ng/ml) over a relatively narrow concentration ra...

I review three different non-perturbative approaches to the three dimensional Nf -flavor Thirring model: the 1/Nf expansion, Schwinger-Dyson equations, and Monte Carlo simulation. Simulation results are presented to support the existence of a non-perturbative fixed point at a chiral symmetry breaking phase transition for Nf = 2 and 4, but not for Nf = 6. Spectrum calculations for Nf = 2 reveal ...

Abstract To improve outcome prediction following subarachnoid haemorrhage (SAH), we sought a biomarker integrating early brain injury and multiple secondary pathological processes in prospective study of 42 non-traumatic SAH patients 19 control individuals. Neurofilament light (NF-L) was elevated CSF serum SAH. NF-L on Days 1–3 post-SAH strongly predicted modified Rankin score at 6 months, inde...

We propose a method for implementing the large-Nc, large-Nf limit of QCD at the effective Lagrangian level. Depending on the value of the ratio Nf/Nc, different patterns of chiral symmetry breaking can arise, leading in particular to different behaviors of the η′-mass in the combined large-N limit. Typeset using REVTEX 1 1. Large-Nc considerations successfully explain many non-perturbative aspe...

Patients with diabetes are at a higher risk of having diabetic foot ulcers (DFUs) or necrotizing fasciitis (NF). The present study aims to examine the clinical characteristics and associated risk factors for lower-extremity amputation (LEA) in patients with DFU complicated by NF.We retrospectively reviewed patients treated at a major diabetic foot center in Taiwan between 2009 and 2014. Of the ...

PURPOSE To investigate the phosphorylation of the heavy neurofilament subunit (NF-H), which could be deeply involved in axonal transport of retinal ganglion cells (RGCs), in an experimental glaucoma model of chronic elevation of intraocular pressure (IOP) in monkeys. METHODS One eye in adult monkeys was randomly selected for laser treatment, and IOP was maintained between 30 and 40 mm Hg thro...

Photoperiod dependent flowering is one of several mechanisms used by plants to initiate the developmental transition from vegetative growth to reproductive growth. The NUCLEAR FACTOR Y (NF-Y) transcription factors are heterotrimeric complexes composed of NF-YA and histone-fold domain (HFD) containing NF-YB/NF-YC, that initiate photoperiod-dependent flowering by cooperatively interacting with CO...

begin{abstract} If $F,D:Rto R$ are additive mappings which satisfy $F(x^{n}y^{n})=x^nF(y^{n})+y^nD(x^{n})$ for all $x,yin R$. Then, $F$ is a generalized left derivation with associated Jordan left derivation $D$ on $R$. Similar type of result has been done for the other identity forcing to generalized derivation and at last an example has given in support of the theorems. end{abstract}

We investigated the role of nuclear factor-κB (NF-κB) and phosphatase and tensin homolog deleted in chromosome 10 (PTEN) in the pathogenesis of osteosarcoma and its relationship with prognosis. Immunohistochemical method was used to detect the expression of NF-κB and PTEN in osteosarcoma and adjacent tissues. RT-PCR was used to detect the expression of NF-κB and PTEN mRNA in osteosarcoma and ad...

States of phosphorylation of neurofilament proteins were examined in the perikarya of rat sensory and motor neurons between 3 and 28 d following either a distal transection [6-7 cm from the L4-L5 dorsal root ganglia (DRG)] or a proximal transection (1-2 cm from the L4-L5 DRG) of the sciatic nerve. Paraffin sections of the right (experimental) and left (control) L4 and L5 DRG from animals with u...