In this study, we proposed to modify mesoporous silica nanoparticles (MSNs) with 3-aminopropyltriethoxysilane (NH2-TES), aminoethylaminopropyltriethoxysilane (2NH2-TES) and 3-[2-(2-aminoethylamino)ethylamino] propyl-trimethoxysilane (3NH2-TES) for binding of cytosine-phosphate-guanosine oligodexynucleotides (CpG ODN), and investigated the effect of different amino groups of MSNs on the CpG ODN ...

The interaction between carbon quantum dots (CQDs) and a single living cell was explored in real time. Here, we provide the quantitative data on the permeability of the HeLa cell membrane in the presence of CQDs with different surface functional groups (CQDs terminated with -OH/-COOH (CQD-OH), -PEG (CQD-PEG), and -NH2 (CQD-NH2)). Although these CQDs have very low toxicity towards HeLa cells, th...

Previously, we identified a core undecapeptide of sapecin B having antimicrobial activity. Based on the structure of this peptide, we systematically synthesized peptides consisting of terminal basic motifs and internal oligo-leucine sequences and examined their antimicrobial activities. Of these peptides, RLKLLLLLRLK-NH2 and KLKLLLLLKLK-NH2 were found to have potent microbicidal activity agains...

In the search of new organometallic precursors, this contribution describes a convenient synthesis to obtain ferrocene-based sulfonyl diamine derivatives. The [(η5-C5H4SO2NH-CH2-CH2-NH2)Fe(η5-C5H5)] (1) and [(η5-C5H4SO2NH-C6H4-NH2)Fe(η5-C5H5)] (2) compounds were prepared by reaction between (η5-C5H4SO2Cl)Fe(η5-C5H5) respective precursor: ethylenediamine or p-phenylenediamine in good yield...

Abstract Laminar flame speeds of ammonia with oxygen-enriched air (oxygen content varying from 21 to 30 vol.%) and ammonia-hydrogen-air mixtures (fuel hydrogen 0 at elevated pressure (1–10 bar) temperature (298–473 K) were determined experimentally using a constant volume combustion chamber. Moreover, laminar helium as an inert measured for the first time. Using these experimental data along pu...

Reactions of the cyclic systems (NPC12)2NS0X and NPC12(NS0X)2 (X = F, Cl, Ph) with NH3 in diethyl ether or acetonitrile at low temperature provide convincing evidence that the P-bonded chlorine atoms are replaced by NH2 groups along a geminal pathway. No disruption of the S-F and S-Ph bonds occurs. Aminolysis of NPC12(NS0C1)2 proceeds to NP(NH2)2(NS0C1)2, followed by decomposition, (NPC12)2NS0C...

Mixed matrix membrane used to selective removal of CO2 was considered as an efficient solution to energy and environmental sustainability. In this study, a MMM that consists of amide functionalized porous coordination polymer filler (MIL-53-NH2) was successfully prepared, which sharply promotes the CO2/N2 selectivity from 44 (neat polymeric membrane) to 75. Remarkably, the positive effect of am...

In 85% of Ewing family tumors, the NH2 terminus of EWS is fused to the DNA-binding domain of FLI1, an ets transcription factor. The resulting chimeric protein is a strong transcriptional activator with transforming activity. We report that EWS and EWS-FLI1 interact via their common NH2 terminus with the COOH terminus of BARD1, a putative tumor suppressor, in vitro and in vivo. Because BARD1 ass...

The structural proteins of Sindbis virus, an enveloped virus which belongs to the Togavirus family, have been subjected to automated Edman degradation using improved techniques. Extensive NH2-terminal sequences of about 50 residues were determined for each of the two membrane glycoproteins. In both cases the NH2 terminus of the molecule was found to be similar in composition to typical water-so...