Molecular docking process was performed to investigate the interactions between synthesized compounds and human epidermal growth factor protein kinase domain EGFR (PDB ID:1M17) cyclin-dependent kinase-2 CDK2 ID:3IG7) proteins. HOMO LUMO orbital energy analysis, quantum chemical calculations were made bioactivity parameters of evaluated. NiII CuII complexes L1H2 L2H2 L3H2, ligands showed higher ...
