Dermatological conditions, such as acne, photoaging, psoriasis, and wounds, have been treated topically with all-trans retinoic acid (ATRA) for many years owing to its anti-inflammatory activity, comedolytic effect, ability increase collagen production. However, common side effects of ATRA known the retinoid reaction can occur. These are countered by encapsulation in solid lipid nanoparticles (...

Differential diagnosis of NLCS includes nevus sebaceous, skin tag or fibroepithelial polyp, neurofibroma, lymphangioma, lipofibroma, focal dermal hypoplasia (Goltz syndrome), lipomatosis, and Michelin tire baby syndrome.[2,4] Histopathological examination helps in the differentiation. There is absence of fat cells in the dermis in skin tag. In lipofibroma skin, appendages are absent in the derm...

A simple and fast capillary electrophoresis method has been developed to determine the amount of piroxicam loaded in a drug delivery system based on nanostructured lipid carriers (NLCs). The entrapment efficiency of the nanostructured lipid carrier was estimated by measuring the concentration of drug not entrapped in a suspension of NLC. The influence of different parameters on migration times,...

Squalene is a triterpene that is an intermediate in the cholesterol biosynthesis pathway. It was so named because of its occurrence in shark liver oil, which contains large quantities and is considered its richest source. However, it is widely distributed in nature, with reasonable amounts found in olive oil, palm oil, wheat-germ oil, amaranth oil, and rice bran oil. Squalene, the main componen...

This paper presents a modified approach for high-resolution, highly squint synthetic aperture radar (SAR) data processing. Several nonlinear chirp scaling (NLCS) algorithms have been proposed to solve the azimuth variance of the frequency modulation rates that are caused by the linear range walk correction (LRWC). However, the azimuth depth of focusing (ADOF) is not handled well by these algori...

Previous reports show ineffective transdermal delivery of ketorolac by nanostructured lipid carriers (NLCs). The aim of the present work was enhancement of transdermal delivery of ketorolac by another colloidal carriers, lipid nanocapsules (LNCs). LNCs were prepared by emulsification with phase transition method and mixed in a Carbomer 934P gel base with oleic acid or propylene glycol as penetr...

Parallel to the highly successful Ericksen-Leslie hydrodynamic theory for the bulk behavior of nematic liquid crystals (NLCs), we derive a set of coupled hydrodynamic boundary conditions to describe the NLC dynamics near NLC-solid interfaces. In our boundary conditions, translational flux (flow slippage) and rotational flux (surface director relaxation) are coupled according to the Onsager vari...

Since the 1930s there have been over a thousand recorded sightings of monsters in Loch Ness, Scotland. The consensus experts is these reports mysterious creatures (known Scottish Highlands folklore as Nessie) mundane or prosaic explanations such hoaxes, wakes, mirages, misidentifications floating objects (e.g., natural debris, boats) and known native fauna deer, otters, diving birds), opposed t...