Regulation of transcription is fundamental to development and physiology, and occurs through binding of transcription factors to specific DNA sequences in the genome. CSL (CBF1/Suppressor of Hairless/LAG-1), a core component of the Notch signaling pathway, is one such transcription factor that acts in concert with co-activators or co-repressors to control the activity of associated target genes...

Unsaturated constant water content triaxial compression tests with suction measurement, using an Imperial College tensiometer, and saturated consolidated undrained were conducted on reconstituted brickearth, a naturally unsaturated clayey silt from London. The results show that the effective stress can be applied to critical state line (CSL) normalized stiffness for brickearth but Bishop's vari...

two hundred and twenty one-day male chicks (ross 308) were used in a completely randomized design with 5 treatments and four replicates each to investigate the effects of the different levels of 0.15, 0.3 and 0.6 percent rosemary extract along with nitrate (27.4 mg sodium nitrate/liter water) in drinking water on growth, some blood parameters and carcass characteristics of broiler chickens. no ...

The role of histamine in the regulation of food and water intake in mammals and birds of the review, this study evaluated the effects of intraperitoneal administration of chlorpheniramine as histamine H1-receptor antagonist, in broiler chicks on feed intake and satiety in water and was hungry. 32 male Ross broiler chicks reared in groups of four weeks, 16 samples (control and test) were then in...

The Notch/CSL pathway plays an important role in skin homeostasis and carcinogenesis. CSL, the key effector of canonical Notch signaling endowed with an intrinsic transcription repressive function, suppresses stromal fibroblast senescence and Cancer Associated Fibroblast (CAF) activation through direct down-modulation of key effector genes. Interacting proteins that participate with CSL in this...

Continuous Spontaneous Localization (CSL) is one possible explanation for dynamically induced collapse of the wave-function during a quantum measurement. The collapse is mediated by a stochastic non-linear modification of the Schrödinger equation. A consequence of the CSL mechanism is an extremely tiny violation of energy-momentum conservation, which can, in principle, be detected in the labora...

This experiment was conducted to determine the effect of aqueous extract of Telfairia occidentalis (Fluted Pumpkin) leaf on the performance and haematological indices of starter broilers. A total of 200, 8-day-old broiler chicks were randomly allotted to five (5) treatments, each with 4 replicate groups containing 10 chicks and fed with standard starter broiler diets. Telfaria occidentalis leav...

In a market undergoing constant evolution, the production of chicken meat that consumers would perceive as "natural" and "animal friendly" is crucial. The use of probiotics in rurally reared chickens could represent a major opportunity to achieve mutual benefit for both the industry and consumers. A total of 264 male Kabir chicks were randomly distributed to one of 2 dietary treatments: the L g...

Feed deprivation is used in the layer industry to induce molting and stimulate multiple egg-laying cycles in laying hens. Unfortunately, the stress involved increases susceptibility to Salmonella enteritidis (SE), the risk of SE-positive eggs, and incidence of SE in internal organs. Leghorn hens over 50 wk of age were divided into 4 treatment groups of 12 hens each in experiment 1 and 3 treatme...

We present CCMC (Conditional CSL Model Checker), a model checker for continuous-time Markov chains (CTMCs) with respect to properties specified in continuous-time stochastic logic (CSL). Existing CTMC model checkers such as PRISM or MRMC handle only binary CSL until path formulas. CCMC is the first tool that supports algorithms for analyzing multiple until path formulas. Moreover, CCMC supports...