UNLABELLED Motivation. Protein design aims to identify sequences compatible with a given protein fold but incompatible to any alternative folds. To select the correct sequences and to guide the search process, a design scoring function is critically important. Such a scoring function should be able to characterize the global fitness landscape of many proteins simultaneously. RESULTS To find o...

Emerging markets contain the vast majority of the world’s population. Despite the huge number of inhabitants, these markets still lack a proper finance infrastructure. One of the main difficulties felt by customers is the access to loans. This limitation arises from the fact that most customers usually lack a verifiable credit history. As such, traditional banks are unable to provide loans. Thi...

This study is an inclusive scoping review of the literature relating to outcome prediction in adult non-trauma emergency patients, in order to identify the number and range of risk scores developed for acutely ill adults and to identify the outcomes these scores predict. The data source used was Medline 1950-2009. To be eligible for inclusion, papers had to detail an assessment tool, wholly or ...

This paper analyzes probability judgments about properties that can take multiple values (i.e., monadic polytomous events). It extends previous work on pattern-based deviations from standard (extensional) probabilities. Pattern-probabilities are formalized in Bayesian Logic (BL) and should be applicable when testing the overall adequacy of alternative logical hypotheses while allowing for excep...

Dichotomous thinking is a propensity for individuals to understand events as opposites, in binary way. There are currently two inventories that accurately measure this construct, the Thinking Inventory, and Eating Disorders Scale. The present study aimed carry out review process compile all empirical studies have made use of either these instruments. To achieve goal, we carried scoping review. ...

Stochastic processes defined by a general Langevin equation of motion where the noise is the nonGaussian dichotomous Markov noise are studied. A non-Fokker-Planck master differential equation is deduced for the probability density of these processes. Two different models are exactly solved. In the second one, a nonequilibrium bimodal distribution induced by the noise is observed for a critical ...

the bender-gestalt test was given to thirty mentally-retarded psychiatric patients. the mean, standard deviation, and standard error were 56.73, 26.25, and 4.80 respectively. rotation was the most frequent major deviation which occurred in all the designs. design # 7 was the most difficult one to be reproduced in the sample. this design by itself, was subject to 47% of distortion, 79% of omissi...

conclusions the mgap scoring system can be used as an appropriate scoring system to predict mortality in triage trauma patients. results patients were divided into three groups : scores of less than 18, 18 - 22 and greater than 22; in which the mortality rates were 75.2%, 9.5% and 0.1%, respectively (p < 0.0001). the best cut-off point was 22 in our study, and the mgap scoring system had 93.7% ...

background: multiple severity scoring systems have been devised and evaluated in adult sepsis, but a simplified scoring model for pediatric sepsis has not yet been developed. this study aimed to develop and validate a new scoring model to stratify the severity of pediatric sepsis, thus assisting the treatment of sepsis in children. methods: data from 634 consecutive patients who presented with ...

background: high-energy ionizing radiation is harmful and changes the genetic makeup of dna, which can lead to increased risk of cancer. thus, the exposure of radiation dose should be under control and limited. ionizing radiation might lead to some chromosome aberrations like dicentric. there is a strong relation between the frequency of dicentric chromosome in metaphase, and the received dose....