In the modern times, vesicular system is a well-known carrier for delivery of drugs. They can carry both lipophilic and hydrophilic Proniosomes are vital member novel drug carriers. The present study was aimed to develop prepare Metronidazole Benzoate loaded proniosomes with different ratios cholesterol non-ionic surfactants prolong release on topical administration. By slurry method, about fou...

Zeolite coated quartz crystal microbalance (QCM) is proposed as an efficient sensor for the detection of ethanol at room temperature. In this work, three zeolites DaY, ZSM-5, and BEA were investigated in order to determine most adsorbent sensing The performances found be mostly influenced by acid site density zeolite's pore size. QCM exhibited best with a high relative frequency shift from 9.0 ...

The aim of this study was to synthesize amphiphilic semi-IPN hydrogels based on acrylic acid (AA) and chitosan (CS) using AIBN as an initiator N,N?methylene bis acrylamide a crosslinking agent. swelling behavior the evaluated at variety pH values, temperature, salinity media time, mechanism investigated Fickian diffusion Schott's 2nd-order-kinetics models. FTIR spectroscopy used confirm synthes...

The dissolution mechanism of rubbery polymers was analyzed by dividing the penetrant concentration field into three regimes that delineate three distinctly different transport processes. The solvent penetration into the rubbery polymer was assumed to be Fickian. The mode of mobility of the polymer chains was shown to undergo a change a t a critical penetrant concentration expressed as a change ...

Objective: The present study was an attempt to develop alternative dosage form for the existing conventional oral, parenteral proton pump inhibitor (PPI) as transdermal patches treating peptic ulcers. Methods: Transdermal of PPI were prepared using HPMC E5 with PVP K 30 and Eudragit L100 polymers in different ratios by a solvent evaporation method. All formulated subjected various evaluation pa...

This paper investigates the dynamics of a model two chemostats connected by Fickian diffusion with bounded random fluctuations. We prove existence and uniqueness non-negative global solution as well compact absorbing attracting sets for solutions corresponding system. After that, we study internal structure set to obtain more detailed information about long-time behavior state variables. In suc...

Monte Carlo (MC) simulations of transport in random porous networks indicate that for high variances of the lognormal permeability distribution, the transport of a passive tracer is non-Fickian. Here we model this non-Fickian dispersion in random porous networks using discrete temporal Markov models. We show that such temporal models capture the spreading behavior accurately. This is true despi...

This article investigates and compares the effects of hydrothermal aging on carbon fibre / Elium™ thermoplastic composite vinylester thermoset for marine application. Accelerated tests are performed by immersion in deionised water at 70 °C. Water diffusion, monitored regular weighing, shows that both composites as well resin exhibit non-Fickian behaviour. Analytical models proposed to fit exper...

Floating matrix tablets of norfloxacin were developed to prolong gastric residence time, leading to an increase in drug bioavailability. Tablets were prepared by the wet granulation technique, using polymers such as hydroxypropyl methylcellulose (HPMC K4M, HPMC K100M) and xanthan gum. Tablets were evaluated for their physical characteristics, viz., hardness, thickness, friability, and mass vari...