UNLABELLED This study evaluated the effects of low-dose cisplatin plus 89Sr versus 89Sr alone in the treatment of painful bone metastases from prostate cancer, addressing both pain palliation and cytostatic effects. METHODS Seventy patients with metastatic hormone-refractory prostate cancer were randomized into 2 groups: One group (arm A) received 148 MBq 89Sr plus 50 mg/m(2) cisplatin, and t...

In recent decades, there has been an increase in the prevalence and medical social burden of osteoarthritis (OA) nonspecific back pain all countries world. The First Multidisciplinary Bilateral Russia-Uzbekistan Expert Council presented innovations prognosing, personalized prevention adjuvant therapy degenerative-dystrophic diseases joints spine, evidence base for effectiveness safety use drugs...

Musculoskeletal pain frequently occurs without particular clinical findings. Pain per se may be determined by factors other than those indicating a clinical disorder. The authors examined the prevalence and determinants of clinically diagnosed chronic rotator cuff tendinitis and self-reported nonspecific shoulder pain. The Health 2000 survey, carried out in 2000-2001 in Finland, included a nati...

conclusions this study showed that a pneumatic arm tourniquet as an adjunct to ivra provides acceptable analgesia following the deflation of the double- cuff tourniquet for relieving surgical pain. results the mean operation time after the deflation of the double-cuff tourniquet was 20.12 ± 6.1 minutes. moreover, the mean nrs for the post-deflation time was insignificant (nrs = 2), and only one...

The purpose of this study was to evaluate the efficacy of a specific 8-week exercise rehabilitation program as an intervention to treat recurrent nonspecific low back pain in adolescents. A randomized controlled trial involving 54 adolescents (14.6 +/- 0.6 years) who suffered from recurrent nonspecific low back pain participated in either the exercise rehabilitation program or a control conditi...

BACKGROUND Chronic low back pain is one of the four most common diseases in the world with great socioeconomic impact. Supervised exercise therapy is one of the treatments suggested for this condition; however, the recommendation on the best type of exercise is still unclear. The Pilates method of exercise is effective in reducing pain and disability in these patients, as well as the analgesia ...

OBJECTIVE We aimed to assess whether the risk factors for severe shoulder pain, especially exposure to arm elevation, were still relevant after a 12-year follow-up, even following retirement. METHODS All men participating in the ARPEGE ancillary study of the GAZEL cohort (followed-up since 1989) and who answered the 1994 or 1995 general GAZEL self-administered question...