OBJECTIVE To identify risk factors for mortality in neonates with meconium aspiration syndrome. METHODS All neonates (2004-2010) with meconium aspiration syndrome, irrespective of gestation were included. Risk factors were compared between those who died and survived. RESULTS Out of 172 included neonates, 44 (26%) died. Mean (SD) gestation and birth weight were 37.9 (2.3) weeks and 2545 (64...

Abstract Purpose To examine the association of maternal bone markers [sclerostin, soluble receptor activator nuclear factor-?B ligand (sRANKL), osteocalcin, 25-hydroxyvitamin D3] with fetal intra-abdominal and subcutaneous adipose tissue deposition birthweight during normal pregnancy. Methods One hundred pregnant women (aged 30.4 ± 5.6 years, mean SD) prepregnancy body mass index = 24.1 4.6 kg/...

To evaluate the role of insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs) in excessive fetal growth (macrosomia) in diabetic pregnancy, 84 insulin-treated diabetic mothers and their infants were tested for serum concentrations of IGF-I, IFG-II, and IGFBP-1, -2 and -3. These parameters were correlated with the birth weight of neonates and placental weight. IGF-I and II levels ...

the risk of nephrocalcinosis (nc) in prctcrtn neonates is considerable, but conflicting numbers arc given for the actual incidence (i o•65(~..~)). furosemide induced hypcrcalciuria is said to be the main risk factor. we assessed prospectively the incidence, causes and outcome of nc in very low birth weight (less than 1500 g) prctcrm neonates by serial renal ultrasound scans and urine analysis. ...

Background: Determining the prevalence and risk factors of thrombocytopenia among neonates enables us to prevent the inevitable and sometimes irreversible complications. In this study we aimed to survey the frequency of thrombocytopenia and its demographic features and risk factors. Materials and methods: In this cross sectional study the platelet counts of 364 neonates admitted to neonatal ...

BACKGROUND Many centers in Israel still use pre-1970 reference data for neonatal weight, length and head circumference. A recently published population-based reference overestimated the weight of premature infants. OBJECTIVE To develop a national reference for birth weight, birth length and head circumference by gestational age for singleton infants in Israel. METHODS Data were collected on...

BACKGROUND The impact of prenatal exposure to cadmium (Cd) on birth outcomes is an area of concern. This study aimed to assess an impact of prenatal Cd exposure on birth outcomes in distinct coastal populations of South Africa. METHODS Cadmium was measured in maternal blood (CdB) (n = 641), cord blood and in maternal urine (n = 317). This investigation assessed the associations between CdB (n...

OBJECTIVE To investigate the potential value of combined screening by maternal characteristics and medical history (maternal factors), estimated fetal weight (EFW), uterine artery pulsatility index (UtA-PI), mean arterial pressure (MAP) and serum levels of placental growth factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1) at 30-34 weeks' gestation in the prediction of delivery of sm...

BACKGROUND Fetal growth impacts cardiovascular health throughout postnatal life in humans. Various animal models of intrauterine growth restriction exhibit reduced heart size at birth, which negatively influences cardiac function in adulthood. The mechanistic target of rapamycin complex 1 (mTORC1) integrates nutrient and growth factor availability with cell growth, thereby regulating organ size...

Background:Respiratory Distress syndrome is the most common respiratory disease in premature neonate and the most important cause of death among them. We aimed to investigate factors to predict successful or failure of INSURE method as a therapeutic method of RDS.Methods:In a cohort study,45 neonates with diagnosed RDS and birth weight lower than 1500g were included and they underwent INSURE fo...