In the US alone, roughly 1.4 million patients undergo operations requiring arterial prostheses annually (1). Tissue engineering (TE) represents a potential means to construct functional small diameter vascular grafts in situations where autologous tissue is unavailable and conventional synthetic materials fail. While initial results with many of the TE vascular grafts (TEVGs) constructed to dat...

Evenepoel, Pieter, Dirk Claus, Benny Geypens, Martin Hiele, Karen Geboes, Paul Rutgeerts, and Yvo Ghoos. Amount and fate of egg protein escaping assimilation in the small intestine of humans. Am. J. Physiol. 277 (Gastrointest. Liver Physiol. 40): G935–G943, 1999.—Studies attempting to evaluate protein assimilation in humans have hitherto relied on either ileostomy subjects or intubation techniq...

Manfridi, Alfredo, Dario Brambilla, and Mauro Mancia. Stimulation of NMDA and AMPA receptors in the rat nucleus basalis of Meynert affects sleep. Am. J. Physiol. 277 (Regulatory Integrative Comp. Physiol. 46): R1488–R1492, 1999.—The nucleus basalis of Meynert (NBM), a heterogeneous area in the basal forebrain involved in the modulation of sleep and wakefulness, is rich in glutamate receptors, a...

Prinz, Christian, Robert Zanner, Markus Gerhard, Sabine Mahr, Nina Neumayer, Barbara Höhne-Zell, and Manfred Gratzl. The mechanism of histamine secretion from gastric enterochromaffin-like cells. Am. J. Physiol. 277 (Cell Physiol. 46): C845–C855, 1999.— Enterochromaffin-like (ECL) cells play a pivotal role in the peripheral regulation of gastric acid secretion as they respond to the functionall...

RAGAVENDRA R. BALIGA,1 DAVID R. PIMENTAL,1 YOU-YANG ZHAO,2 WILLIAM W. SIMMONS,1 MARK A. MARCHIONNI,3 DOUGLAS B. SAWYER,1 AND RALPH A. KELLY1 1Cardiovascular Division, Brigham and Women’s Hospital and Harvard Medical School, Boston 02115; 3Cambridge Neurosciences, Cambridge, Massachusetts 02139; and 2Department of Medicine, University of California at San Diego School of Medicine, La Jolla, Cali...

Boushey, Robin P., Bernardo Yusta, and Daniel J. Drucker. Glucagon-like peptide 2 decreases mortality and reduces the severity of indomethacin-induced murine enteritis. Am. J. Physiol. 277 (Endocrinol. Metab. 40): E937–E947, 1999.—Glucagon-like peptides (GLPs) are secreted from enteroendocrine cells in the gastrointestinal tract. GLP-1 actions regulate blood glucose, whereas GLP-2 exerts trophi...

Kastin, Abba J., and Victoria Akerstrom. Entry of CART into brain is rapid but not inhibited by excess CART or leptin. Am. J. Physiol. 277 (Endocrinol. Metab. 40): E901– E904, 1999.—Cocaineand amphetamine-regulated transcript (CART) is a new anorectic peptide found in the brain and periphery. It is closely associated with leptin, an anorectic agent saturably transported across the blood-brain b...

R. L. EMANUEL,1 J. S. TORDAY,2 Q. MU,3 N. ASOKANANTHAN,3 K. A. SIKORSKI,3 AND M. E. SUNDAY3 1Department of Medicine, Children’s Hospital and Harvard Medical School, and 2Department of Pathology, Children’s Hospital, Brigham & Women’s Hospital, and Harvard Medical School, Boston, Massachusetts 02115; and 3Department of Pediatrics, Harbor-University of California, Los Angeles Medical Center, Torr...

CA Corresponding Author Te l/fax : (+55 ) 16 6232792 Email: shfe rre [email protected] N-NITRO-L-A RG ININE m ethyl este r (L-NAME) has been used ex tensive ly as a paradigm atic in h ibitor of NO synthase and has been show n to cause an tinociception in several ex perim ental m odels. We describe here how L-NAME produced a dose-dependen t an tinociceptive effect when in jected intraperitoneally in...

an Appropriate Basis for Nuclear Worker Compensation? Wakeford (2003) and Little (2003) wrote in response to our comments about the use of A-bomb survivor studies as a basis for U.S. nuclear worker compensation decisions (Wing and Richardson 2002). Wakeford (2003) disagrees with our statement (Wing and Richardson 2002) that there is discrepancy between childhood cancer risk estimates from in ut...