Secondary hyperparathyroidism is a complication of chronic kidney disease, and it develops due to abnormal regulation of calcium and phosphate homeostasis (1). Various factors interact in its development. They are consist of decrease kidney synthesis of 1,25-dihydroxyvitamin D, the, phosphorus retention and impaired calcemic response to parathyroid hormone (1,2). Hence, increasing of parathormo...

BACKGROUND Secondary hyperparathyroidism is a common feature in patients with chronic kidney disease. Its serious clinical consequences include renal osteodystrophy, calcific uremic arteriolopathy, and vascular calcifications that increase morbidity and mortality.Reduced synthesis of active vitamin D contributes to secondary hyperparathyroidism. Therefore, this condition is managed with activat...

RATIONALE Acute kidney injury (AKI) with hyperparathyroidism caused by nitrite was rare, and renal function and parathyroid hormone (PTH) decreased to normal range after therapy. PATIENT CONCERNS Acute kidney injury was diagnosed in a 40-year-old male with hyperparathyroidism and cyanosis of his hands and both forearms. DIAGNOSES The patient ate some recently pickled vegetables, and he expe...

Hyperparathyroidism, either secondary or tertiary, is a major complication of end stage renal disease (ESRD). It can result in renal bone disease if left untreated. Although surgical parathyroidectomy remains the treatment of choice, the appropriate therapy to treat hyperparathyroidism in specific patient groups such as tracheostomized patients has not been elucidated. We present a case of seco...

Brown tumors are osteolytic bone lesions that occur as a result of persistent hyperparathyroidism. They usually appear late in the natural history of the disease and are currently very rare due to an earlier diagnosis of primary hyperparathyroidism. We present the case of a 53-year-old female with a 2-month history of bitemporal hemianopsia and diplopia. A computed tomography showed an osteolyt...

Cardiac calcification usually occurs in patients with end-stage renal disease. However, rapid progression of cardiac calcification is rarely associated with secondary hyperparathyroidism of end-stage renal disease. We report a patient with end-stage renal disease who showed moderate left ventricular hypertrophy at the first echocardiography, and showed severe myocardial calcification and severe...

Dihydroxyvitamin D downregulation of TGFalpha/EGFR expression and growth signaling: a mechanism for the antiproliferative actions of the sterol in parathyroid hyperplasia of renal failure. J Steroid Biochem Mol Biol 2004; 89–90: 507–511 27. Sato T, Tominaga Y, Ueki T et al. Total parathyroidectomy reduces elevated circulating fibroblast growth factor 23 in advanced secondary hyperparathyroidism...

Abstract Parathyroid scintigraphy is an imaging technique that uses gamma-emitting radionuclide to locate hyperfunctioning parathyroid glands in patients with hyperparathyroidism. It valuable for preoperative assessment before parathyroidectomy, which a curative surgery most cases of primary hyperparathyroidism and some secondary There are several different techniques scintigraphy. In general, ...

To compare the role of 99mTc-MIBI SPECT-CT image and US in reoperation of persistent secondary hyperparathyroidism patients. A total of 8 persistent secondary hyperparathyroidism patients underwent parathyroidectomy. The sensitivity and accuracy of US and 99mTc-MIBI images before operation were determined. 9 of 14 surgical resection tissues from 8 persistent secondary hyperparathyroidism patien...