POEMS syndrome is a rare multisystem disorder that clinically manifests as paraneoplastic and monoclonal plasma cell dyscrasia. Its acronym derived from its principal characteristics: polyneuropathy, organomegaly, endocrinopathy, M proteins, skin changes. Here, case of was reported also having features Castleman disease. A 43-year-old man admitted with weakness all four limbs, tingling, heavine...

Dr. Fabrizio Di Stani – Dipartimento di Scienze Neurologiche / Università di Roma “La Sapienza” Roma, Italy. E-mail: [email protected] Cluster headache (CH) is characterised by attacks of severe unilateral pain in the orbital, supraorbital and/or temporal areas that last from 15 to 180 min, with recurrence up to 8 times daily and accompanied by ipsilateral autonomic symptoms. Althoug...

In this article three different intramuscular injection procedures used to treat headache pain are reviewed. These procedures, occipital nerve blocks, cervical injections and trigger point injections, are described and the supporting litera-

BACKGROUND Refractory chronic migraine affects approximately 4% of the population worldwide and results in severe pain, lifestyle limitations, and decreased quality of life. Occipital nerve stimulation (ONS) refers to the electric stimulation of the distal branches of greater and lesser occipital nerves; the surgical technique has previously been described and has demonstrated efficacy in the t...