Occupational exposure limits for unstudied pharmaceutical synthetic intermediates are often established under the assumption that penultimate and near-ultimate intermediates have the same structure-activity and dose-response as the ultimate active pharmaceutical ingredient (API). This is seldom the case because moieties that render biological activity to the API are often protected or modified ...

The purpose of this study is to analyze the results of construction accidents occurred from 2011 to 2015 in Korea. The annual reports from the Ministry of Employment and Labor, Korea (MOEL), and the annual reports from the Statistics Korea were used for the analysis in this study. The gender, age, company size and accident types were chosen as a category to analyze the trend of various occupati...

BACKGROUND Fieldwork education is a core part of all occupational therapy curriculums around the world to enable the students meet minimum competencies required for their professional life. Student experience is a valuable source to explore the nature of fieldwork training and plan more efficient curriculums in the future. This study aimed to explore the students' experiences in the first field...

BACKGROUND The use of occupational cohort studies to assess the association of benzene and lymphoma is complicated by problems with exposure misclassification, outcome classification, and low statistical power. OBJECTIVE We performed meta-analyses of occupational cohort studies for five different lymphoma categories: Hodgkin lymphoma (HL), non-Hodgkin lymphoma (NHL), multiple myeloma (MM), ac...

A study of published work was carried out in a search for evidence of a causal role for parental occupational exposure in the origin of structural and functional defects of the central nervous system (CNS) in children. Studies that consider this topic are scarce and mostly refer to broad categories of exposures and effects. Non-occupational studies referring to environmental exposure of humans ...

The International Classification of Functioning, Disability and Health (ICF) is intended to provide a framework for practitioners. A client-centred ICF-based assessment (ICF-A) was developed to be used by occupational therapists in problem identification. The aim was to evaluate the ICF-based assessment (ICF-A) focusing on the examination of its utility on the basis of occupational therapists' ...

BACKGROUND Occupational exposure to blood and body fluids (BBFs) is a hazard of many occupations, particularly hospital-based health care providers. However, non-hospital-based health care workers (HCWs) and other personnel not providing health care are also at risk. AIMS To present the results of surveillance of accidental exposure to BBFs among non-hospital-based French military personnel b...

OBJECTIVES The aim was to investigate the variation in risk of breast cancer between occupational groups with a focus on white-collar and blue-collar workers and to investigate to what extent the differences were explained by risk factors related to reproduction and lifestyle. METHODS Between 1991 and 1996, 14 119 women born between 1923 and 1950 and residents of Malmö, Sweden, were included ...

BACKGROUND U.S. occupational lead standards have not changed for decades, while knowledge about lead's health effects has grown substantially. OBJECTIVE The objective of this analysis was twofold: to estimate the attributable annual societal costs of health damages associated with occupationally lead-exposed U.S. workers and, more broadly, to develop methods for a fuller valuation of health d...

OBJECTIVES The objective of this study was to compare occupational variation of the risk of bladder cancer in the Nordic countries and Canada. METHODS In the Nordic Occupational Cancer study (NOCCA), 73 653 bladder cancer cases were observed during follow-up of 141.6 million person-years. In the Canadian Census Health and Environment Cohort (CanCHEC), 8170 cases were observed during the follo...