THE AIM The aim of this study was to assess general and ocular profiles of patients with single-localisation changes in visual field. MATERIAL AND METHODS The study group consisted of 215 Caucasian patients with normal-tension glaucoma with scotoma on single localisation or with preperimetric glaucoma. During regular follow-up visits, ophthalmic examination was carried out and medical history...

Ocular and/or vision defects are one of the commonest reasons for the referral of young children to hospital. In a survey of a birth cohort in one health district, 7.1% of children were diagnosed as having such defects by their fifth birthday; 2.1% were detected before the age of 2 years, and 5.1% between 2 and 5 years. Up to the age of 2 years, low birthweight children and those who require po...

PURPOSE To evaluate the role of umbilical cord serum therapy in cases of acute ocular chemical burns. METHODS In a double-blind prospective randomized controlled clinical study, 33 eyes of 32 patients with acute ocular chemical burns of grade III, IV, and V severity were randomized into three groups: umbilical cord serum (n = 12), autologous serum (n = 11), and artificial tears (0.5% HPMC+0.3...

Background: Steven-Johnson syndrome is one of life-threatening skin abnormality. SJS complication involve multiorgan disfunction such as mucosa, ocular, respiration, and digestive tract. Around 30- 50% patient experience chronic ocular sequel, which concludes progressive symblepharon, margo palpebral keratinization, trichiasis, entropion, corneal pannus, dry eye syndrome, persistent epithelial ...

Background: Tolmetin (Tol) is a pyrrole acetic acid derivative that acts as a highly effective topical anti-inflammatory agent. Topical administration of Tol is effective for the management of ocular inflammations.The aim of this study was to formulate and improve a topical ophthalmic delivery system of Tol. Materials and methods: In the present study, ocular inserts of Tol were prepared using ...

Background: Behcet syndrome is a recurrent inflammatory disorder that frequently involves the ocular system. The purpose of this study was to determine the frequency of ocular involvement in cases of Behcet's disease in Babol, north of Iran. Methods: From April 2003 to December 2009, 100 cases of behcet's disease who were admitted at the Department of Ophthalmology and Internal Medicine of Babo...

We highlight a new wave of paediatric ocular surface injuries. In 2001 the cleaning products industry produced liquid capsules for fabric detergents. Last year chemical injuries associated with these capsules accounted for 40% of ocular chemical injuries in children under the age of 5 at this hospital. Guy’s and St Thomas’ Poisons Unit received 192 enquires related to the capsules during 2007-8...

BackgroundEthambutol (EMB) is one of the first-line anti-tuberculosis therapy. One its precarious side effects ethambutol-induced optic neuropathy (EON). The ocular manifestations EON include painless loss central vision and cecocentral scotomas in visual field. Case DescriptionA 60-year old man presented with gradual since 3 months prior to visit. accompanying symptoms were frequent headache w...

We evaluated the dose relationship between the antiproliferative and toxic effects of 5-fluorouracil (5-FU) on the ocular surface epithelium following experimental corneal epithelial wounding in rabbits. Central corneal epithelial defects 8 mm in diameter were made using n-heptanol. 5-FU (0.05 mg, 0.5 mg, or 5.0 mg per day in divided doses) or saline was applied topically for up to 18 days begi...