Rosacea is a chronic inflammatory skin disease characterized by recurrent episodes of facial flushing, erythema, papules, pustules, and telangiectasia. More than half of all rosacea patients may have ocular symptoms. Rosacea is associated with certain digestive diseases, such as gastritis, hypochlorhydria, or a number of jejunal mucosal abnormalities, and many patients have Helicobacter pylori ...

AIMS To describe the clinical course and treatment of Haemophilus influenzae associated scleritis. METHODS Retrospective case series. RESULTS Three patients developed scleritis associated with ocular H influenzae infection. Past medical history, review of systems, and laboratory testing for underlying collagen vascular disorders were negative in two patients. One patient had arthritis assoc...

PURPOSE To report an unusual case of multifocal bacterial keratitis that despite success-ful treatment caused chronic ocular hypertension. METHODS A 67-year-old woman with unilateral multifocal keratitis and no previous ocular pathology was admitted to our hospital. Corneal scrapings and conjunctival samples were obtained for culture and the patient received intensive therapy with fortified v...

OBJECTIVE To characterize the histologic alterations in the ocular globe of mice infected with eggs of Toxocara canis, during both the acute and chronic stages of the infection. METHOD Performance of an experimental, prospective study in vivo, with right and left ocular globes [using 5 groups of 4 mice in each study; 2 white (A/J) and 2 black (C57/BL)], infected by the intravenous injection o...

West Nile Virus (WNV), first isolated in 1937 in the West Nile district of Uganda, is a single-stranded RNA flavivirus. It is a member of the Japanese encephalitis serogroup. WNV infection is a zoonotic disease transmitted by a mosquito vector (type Culex), with wild birds serving as its reservoir. The disease is endemic in Europe, Australia, Asia, Africa, and North and Central America since it...

Staphylococcal bacteremia is an important clinical entity. A 74-year-old lady presented with an isolated staphylococcal ocular infection; this was treated with a short course of antibiotics, a prolonged course of steroids, and discharge from hospital with outpatient clinic followup. She represented three weeks later to the emergency department with back pain, raised inflammatory markers, and po...

A potent interferon inducer, synthetic polyinosinic acid-polycytidylic acid complex (poly I:C), was used prophylactically and therapeutically in experimental ocular Toxoplasma infections in rabbits. Daily intravenous injections of poly I:C alone or when combined with daily subconjunctival injections of the inducer delayed the appearance of conjunctivitis, corneal opacity, and iritis in Toxoplas...

Protothecosis is an uncommon disease caused by a unicellular algae primarily found in organic matter, which affects humans, cattle, dogs, and cats, with reserved to poor prognosis. The infection typically begins the gastrointestinal tract, presenting as refractory diarrhea that persists for months before progressing systemic infection, involving other organs such eyes. objective of this study w...

AIMS To evaluate the role of nitric oxide (NO) in ocular involvement during systemic toxoplasmosis. METHODS C57B1/6 mice were infected with Toxoplasma gondii strain ME49. The synthesis of NO was inhibited by an intraperitoneal injection of aminoguanidine every 8 hours, starting on the day of infection. Control infected mice received phosphate buffered saline vehicle alone. After 14 days, the ...

The epidemiological and clinical features of recurrent herpes simplex virus ocular infection (RHSV) were studied. Of 108 patients with primary herpes simplex virus ocular infection (PHSV) who were followed up for two to 15 years 35 (32%) suffered one or more recurrent attacks. The recurrence rate was significantly higher in patients under 20 years of age, but there was no significant difference...