Cystinosis is a rare autosomal recessive disorder characterized by the accumulation of cystine within the cells of different organs. Infantile nephropathic cystinosis is the most common and severe phenotype. With the success of renal transplantation, these patients are now living longer and thus more long-term complications within different organs are becoming apparent. Ophthalmic manifestation...

Resveratrol, a naturally occurring plant polyphenol found in grapes, is the principal biologically active component in red wine. Clinical studies have shown that resveratrol due to its potent anti-oxidant and anti-inflammatory properties are cardio-protective, chemotherapeutic, neuroprotective, and display anti-aging effects. Oxidative stress and inflammation play a critical role in the initiat...

BACKGROUND To compare life span of persons with and without ocular pseudoexfoliation syndrome (PES). METHODS The study is based on an epidemiological survey conducted in Sør-Trøndelag county, Norway, in 1985-86. All inhabitants over 64 years of age (2109 individuals) were invited. Mortality information was obtained from The Norwegian Institute of Public Health in 2014, by which time 99% of th...

Cytomegalovirus (CMV) retinitis is the commonest ocular complication of AIDS and the prevention of recurrence has been dependent on lifelong maintenance treatment. Recently there has been a dramatic downturn in the number of new cases of CMV retinitis, which has been attributed to the introduction of highly active antiretroviral therapy (HAART) and subsequent improved survival. Whereas paucity ...

Purpose: We report an unusual case of trabecular carcinoid of the ovary with orbital involvement. Methods: We encountered a 49-year-old woman with a complaint of bilateral proptosis. Ocular examination revealed severe bilateral proptosis and signs of corneal exposure. Orbital CT scan showed massive enlargement of extraocular muscles and optic nerve compression. The patient medical history showe...

from 1986 to 1996, 1020 renal transplants were performed at our center. the purposes of this study were. 1) to evaluate the patient and graft survival rates and 2) to see if some donors and recipient characteristics such as age, sex and relationship had any effects on graft survivals. 571 transplants were from living related donors (lrd) and 446 from living unrelated donors (lud). 65.9% of reci...

background: breast cancer arising in young patients (≤ 40 years) is being considered as a distinct clinical entity with more aggressive tumor features and poorer survival. our aim was to assess the impact of age on survival among a large group of iranian women diagnosed with breast cancer. methods: in a cross-sectional study, demographic and clinicopathological characteristics of patients with ...

Introduction: Chronic renal disease compromises of several renal involvements and several causative risk factors such as debates mellitus, hypertension, and old age. Ocular involvement seems to be related to chronic renal failure and hemodialysis as indicated by different studies. The aim of this study was the evaluation of prevalence of ocular manifestation in hemodialysis patients of Hamadan ...