Background: One of the most common symptoms of COVID-19 infection is Olfactory Dysfunction (OD). Objectives: This study aims to investigate OD and phantosmia in COVID-19 cases from northern Iran. Materials & Methods: In this cross-sectional study, participants were 400 patients with COVID-19 infection in Rasht, Iran from March 2019 to September 2020. All the patients were evaluated in terms o...

Olfactory dysfunction is common in Parkinson's disease and is an early symptom, but its pathogenesis remains poorly understood. Hindering progress in our mechanistic understanding of olfactory dysfunction in Parkinson's disease is the paucity of literature about the human olfactory bulb, both from normal and Parkinson's disease cases. Qualitatively it is well established that the neat arrangeme...

Usher Syndrome (USH) is a rare disease with hearing loss, retinitis pigmentosa and, sometimes, vestibular dysfunction. A phenotype heterogeneity is reported. Recent evidence indicates that USH is likely to belong to an emerging class of sensory ciliopathies. Olfaction has recently been implicated in ciliopathies, but the scarce literature about olfaction in USH show conflicting results. We aim ...

Normal functioning of the olfactory system is a prerequisite for the detection of several chemical environmental hazards (e.g., spoiled foods, leaking natural gas, smoke and various airborne pollutants), and for the full appreciation of foods, beverages, flowers, perfumes, spices, the seashore, the mountains, and the seasons of the year. Distortions or loss of smell function can adversely influ...

Abstract Background The coronavirus disease 2019 (COVID-19) pandemic has caused recurring and major outbreaks in multiple human populations around the world. plethora of clinical presentations severe acute respiratory syndrome 2 (SARS-CoV-2) been described extensively, which olfactory dysfunction (OD) was established as an important common extrapulmonary manifestation COVID-19 infection. aim th...

Olfactory dysfunction is an early and common symptom in Parkinson's disease (PD). In an effort to determine whether otherwise unexplained (idiopathic) olfactory dysfunction is associated with an increased risk of developing PD, we designed a prospective study in a cohort of 361 asymptomatic relatives (parents, siblings, or children) of PD patients. A combination of olfactory detection, identifi...

OBJECTIVE Olfactory and emotional dysfunctions are very common in patients with Parkinson's disease (PD). Olfaction and emotions share common neuroanatomical substrates. Therefore, in this study, we evaluated the association between olfactory and emotional dysfunctions in patients with PD. METHODS Parkinson's disease patients who had been assessed for their olfactory function and neuropsychia...

Abstract Background The devastating coronavirus disease (COVID-19) pandemic seemed not yet to cease. Numerous studies regarding its typical sign and symptoms have been done, presenting one of the most promising predictors infection: olfactory dysfunction. Although life-threatening, symptom could decrease one’s quality life, especially if persistent throughout their entire life. Among countless ...

Background: Since its outbreak, the 2019 novel coronavirus (SARS-CoV-2) has been associated withcoronavirus disease (COVID-19). The full spectrum of severity COVID-19 is still unknown.In this study which first report from Iran, we showed that olfactory dysfunction a frequent clinicalmanifestation among patients.Methods: All patients with suspected SARS-CoV-2 infection were admitted to Arak hosp...

Intranasal medications are used to treat various nasal disorders. However, their effects on olfaction remain unknown. Zicam (zinc gluconate; Matrixx Initiatives, Inc), a homeopathic substance marketed to alleviate cold symptoms, has been implicated in olfactory dysfunction. Here, we investigated Zicam and several common intranasal agents for their effects on olfactory function. Zicam was the on...