Stabilitas forklift masih menjadi salah satu perhatian tersebar hingga saat ini, banyak kasus kecelakaan yang disebabkan hilangnya stabilitas membawa beban. Dalam penelitian ini akan dianalisa kestabilan dalam kondisi diam dan pengereman.. Model obyek adalah Forklift TCM FD25T3Z dengan variasi beban kecepatan. Analisa dilakukan untuk mengetahui massa maksimum dapat diterima pengaruh terhadap pe...

The cycles of the water isotopic species (HDO and H2 0) have been incorporated in three atmospheric General Circulation Models (GCMs) with the main objective of predicting the distribution of water stable isotopes in precipitation, The performances of those models are examined for present-day climate through a comparison with existing data available from the IAEA/WMO network established in 1961...

Siliceous ordered mesoporous materials (OMM) are gaining interest as supports for enzyme immobilization due to their uniform pore size, large surface area, tunable pore network and the introduction of organic components to mesoporous structure. We used SBA-15 type silica materials, which exhibit a regular 2D hexagonal packing of cylindrical mesopores of uniform size, for non-covalent immobiliza...

To uptake calcium ions of mitochondria is of significant functional connotation for cells, because calcium ions in mitochondria are involved in energy production, regulatory signals transfer, and mitochondrial permeability transition pore opening and even programmed cell death of apoptosis, further playing more roles in plant productivity and quality. Cytoplasmic calcium ions access into outer ...

Left ventricular assist devices (LVADs) are approved for use in patients in stage D heart failure (HF), either as bridge to transplantation or as permanent (destination) therapy. The optimal timing of LVAD implantation along the continuum of chronic HF is under active investigation. Most patients currently being implanted with LVADs have significant hemodynamic compromise, usually necessitating...

To the Editor: As a fourth-year student at the West Virginia School of Osteopathic Medicine, Lewisburg, I had to choose between pursuing an American Osteopathic Association (AOA)–approved or an Accreditation Council for Graduate Medical Education (ACGME)–accredited residency program. Interestingly, my decision to pursue an ACGME-sponsored position has been met with some resistance. Therefore, I...

Melanoma is potentially a fatal skin malignancy with more than 80,000 new cases in the US annually resulting in nearly 10,000 deaths (www.cancer.gov). Mutations within the MAPK pathway are bona fide oncogenes that are mutated in ~80% of melanoma cases [1,2]. The MAPK pathway consists of a series of proteins that link a growth factor (e.g., EGF) activated plasma membrane receptor tyrosine kinase...

Objective: Evaluating the effect of antenatal betamethasone on the biophysical profile and Doppler indices of umbilical and middle cerebral arteries. Materials and Methods: Twenty-five preterm labor singleton pregnancies (gestational age, 26-34 weeks) were studied prospectively. These patients received two consecutive doses of betamethasone 24 hours apart to accelerate pulmonary maturation. Fet...

Cancer cells share several properties, high proliferation potential, reprogramed metabolism, and resistance to apoptotic cues. Acquiring these hallmarks involves changes in key oncogenes and non-oncogenes essential for cancer cell survival and prosperity, and is accompanied by the increased energy requirements of proliferating cells. Mitochondria occupy a central position in cell life and death...

Neurons strictly rely on proper mitochondrial function and turnover. They possess a high energy requirement which is mostly fueled by mitochondrial oxidative phosphorylation. Moreover the unique morphology of neurons implies that mitochondria need to be transported along the axons to sites of high energy demand. Finally, due to the non-dividing state of neurons, cellular mitosis cannot dilute d...