Glinus oppositifolius is a small herb, widely used in the traditional medicine of Bangladesh in treatment of a variety of diseases and disorders such as insomnia, pain, inflammation, jaundice, and fever. The present study evaluated the sedative and anxiolytic potentials of the ethanol extract of leaves of G. oppositifolius (EEGO) in different behavioral models in mice. The sedative activity of ...

Male and female hooded rats were intraperitoneally injected with 0 (vehicle only), 5 or 10 mg/kg D-cycloserine (DCS) and then individually allowed free access to the arms of a Y maze (acquisition trial), one of which was black and the other white. Their ability to later recognize the arm that had changed from white to black was assessed from the first arm entered, and the number of times the no...

Objective(s): In recent years, nanotechnology has produced new forms of materials that are more effective than their predecessors. Magnesium is an essential element in the human body and certain studies have proved that its deficiency can induce anxiety in animals. In this study, the effect of magnesium oxide nanoparticles (MgO NPs) on anxiety, related behaviors, and interaction between their e...

α-galycoceramide (α-galcer) or the common name of krn7000 is an α-gelasphin derivative. the α-galcer structure consists of a galactose combined with a ceramide in an α-configuration. social isolation (si) has been linked with enhanced inflammation, through modifications in transcriptional pathways linked with glucocorticoid, to stress. our hypothesis is to investigate mediatory role of glucocor...

It has been previously reported that Wistar-Kyoto (WKY) rats may be useful in the study of the biological mechanisms involved in stress-related disorders. In the present study, WKY were treated acutely or chronically (one daily i.p. injection for 22-24 days) with the selective 5-HT reuptake inhibitor and clinically effective antidepressant and anxiolytic fluoxetine (5 and 20 mg/kg) and exposed ...

Incidence of anxiety-like disorders in humans has been shown to decrease with aging; however, it is still under debate whether there are similarities mice, which would support the use mouse models understanding neuronal network changes that regulate behavior aging. One most common tests used assess laboratory animals elevated plus maze (EPM). Although several variables, such as room brightness ...

Background: Toxoplasma gondii is a zoonotic protozoan with worldwide distribution. Recent studies have shown that the transmission of T. facilitated by its ability to modify host’s behavior. Objectives: The present study aimed investigate effect infection on anxiety in an animal model and determine levels cortisol interleukin-17 (IL-17) rats. Methods: In this study, 40 rats were randomly alloca...

BACKGROUND The aim of the present study was to evaluate the anxiolytic properties of the decoction of stem bark of Hallea ciliate in mice. The decoction of Hallea ciliata is used in traditional medicine in Cameroon to treat diseases like anxiety disorders, fever, infantile convulsions and malaria. MATERIALS AND METHODS Stress induced hyperthermia, elevated plus maze, open field and hole-board...

Entries of and time spent in a novel Y-maze arm that had changed from white (during acquisition trials) to black (during retention trials) were investigated in male and female Long-Evans hooded rats after the apparatus had been horizontally rotated through 180 degrees or left undisturbed. Maze rotation reduced responsiveness to this arm in males but not in females. When each arm was associated ...

this article studies the generative grammar approach and some other theories driven from it to lexicon and lexical entries. generative grammar is known as a syntax-based theory, so some aspects of language which have been studied in this theory may have been ignored in other theories. this article shows that more attention has been given to lexicon and lexical entries since 50s. we may claim th...