Introduction: The competence of opiate addicts to give a valid consent to heroin prescription (HP) has been doubted in principle under the assumption that the pathological urge to use heroin would prevent them from reasonably weighing the pros and cons of HP. This study was done to test whether opiate addicts have a differentiated attitude towards HP which would be a basis for an individual dec...

BACKGROUND Given the role of temperament and character dimensions on impulsivity in addicts, the purpose of this study was to temperament and character dimensions: correlates of impulsivity in morphine addicts. OBJECTIVES The aim of this study was to determine and verify the association of temperament and character dimensions with impulsivity in morphine addicts. PATIENTS AND METHODS The re...

Abstract Taking the humoral body as its spatial focus, this article considers how medical writers and practitioners engaged with ‘intoxicants’ both in terms of prescription medicines conceptualization compulsive consumption – or what is often styled by modern ‘addiction’. Focusing first instance on compilers vernacular pharmacopoeia compilations ingredients techniques argues that just sugar, to...

OBJECTIVE Determine the prevalence and compare some genetic markers involved in addictive behavior in a group of addicts to derivative of coca (cocaine/crack) or heroin and a control group of non-addicted people matched for gender, age and ethnicity. METHODS A 120 addicts and 120 non-addicts Colombian male were surveyed and genotyped for 18 polymorphism of the OPRM1, DRD2, DRD4, SLC6A3, SLC6A...

which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Drug dependence is a chronic and often recurrent disorder which is associated with many problems such as AIDS, hepatitis, etc. This disorder requires treatment management over time. Methadone maintenance therapy is one addiction treatment method which prevents not only the...

This study aims to introduce a new approach of a comprehensive paradigm to evaluate brain electrophysiological properties among addicts. Electroencephalographic spectral power as well as amplitudes and latencies of mismatch negativity (MMN), P300, and P600 components were evaluated among 19 male heroin addicts and 19 healthy nonsmoker subjects using a paradigm consisting of three subparadigms, ...

BACKGROUND Despite some evidences about protective or triggering role of opium use in patients with coronary artery disease, the exact role of opium is still under question. The current study aimed to address the relation of opium dependence on the severity and extension of myocardial infarction (MI) and its related mortality. METHODS The study population consisted of 460 consecutive patients...