PURPOSE To compare optic disc perfusion between normal subjects and subjects with glaucoma using optical coherence tomography (OCT) angiography and to detect optic disc perfusion changes in glaucoma. DESIGN Observational, cross-sectional study. PARTICIPANTS Twenty-four normal subjects and 11 patients with glaucoma were included. METHODS One eye of each subject was scanned by a high-speed ...

AGE AND GENDER DIF’FRRRNCIZS IN OPTIC DISC ARR.4, CUF’ AREAANDVERTlCALCW-TO-DI:SCRATIO?THEROlTERDAM STUDY. RAMRAlTAN RSJZ, GA DE WRUYNE’s, M. VAN RJZESv, HOFMAN A.‘, and DE JONG P.T.Q.M.’ Departments of ‘Ophthalmology and aBpidemiology & Biostatistics. Erasmus University Medical School, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands. m To investigate cross-sectionally the association of age ...

AGE AND GENDER DIF’FRRRNCIZS IN OPTIC DISC ARR.4, CUF’ AREAANDVERTlCALCW-TO-DI:SCRATIO?THEROlTERDAM STUDY. RAMRAlTAN RSJZ, GA DE WRUYNE’s, M. VAN RJZESv, HOFMAN A.‘, and DE JONG P.T.Q.M.’ Departments of ‘Ophthalmology and aBpidemiology & Biostatistics. Erasmus University Medical School, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands. m To investigate cross-sectionally the association of age ...

AGE AND GENDER DIF’FRRRNCIZS IN OPTIC DISC ARR.4, CUF’ AREAANDVERTlCALCW-TO-DI:SCRATIO?THEROlTERDAM STUDY. RAMRAlTAN RSJZ, GA DE WRUYNE’s, M. VAN RJZESv, HOFMAN A.‘, and DE JONG P.T.Q.M.’ Departments of ‘Ophthalmology and aBpidemiology & Biostatistics. Erasmus University Medical School, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands. m To investigate cross-sectionally the association of age ...

PURPOSE The defining feature of glaucoma is excavation of the optic nerve head; however, the mechanism of this loss of tissue is not well understood. We recently discovered a copy number variation upstream of matrix metalloproteinase 19 (MMP19) in a large, autosomal dominant pedigree with a congenital malformation of the optic disc called cavitary optic disc anomaly (CODA). Patients with CODA h...

Several ocular findings have been associated with neurofibromatosis type 2 (NF 2) since the identification of this disease as a distinct clinical entity. Juvenile cataracts were reported first, followed by combined pigment epithelial and retinal hamartomas. In a recent report, epiretinal membranes were described in seven of nine patients. Moreover, an association between NF 2 and optic disc gli...

Glaucoma is a pathological condition, progressive neurodegeneration of the optic nerve, which causes vision loss. The damage to the optic nerve occurs due to the increase in pressure within the eye. Glaucoma is evaluated by monitoring intra ocular pressure (IOP), visual field and the optic disc appearance (cup-to-disc ratio). Cup-to disc ratio (CDR) is normally a time invariant feature. Therefo...

PURPOSE We report a case of macroaneurysm on the optic disc, a rare location, accompanied by vitreous hemorrhage in a patient with aortic dissection. METHODS A 60-year-old female with a history of aortic dissection at the age of 51 presented with visual disturbance owing to vitreous hemorrhage in her right eye. During vitrectomy, we found a large macroaneurysm on the optic disc that was beati...

Optic disc detection and segmentation is one of the key elements for automatic retinal disease screening systems. The aim of this survey paper is to review, categorize and compare the optic disc detection algorithms and methodologies, giving a description of each of them, highlighting their key points and performance measures. Accordingly, this survey firstly overviews the anatomy of the eye fu...

This paper proposes an efficient combination of algorithms for the automated localization of the optic disc and macula in retinal fundus images. There is in fact no reason to assume that a single algorithm would be optimal. An ensemble of algorithms based on different principles can be more accurate than any of its individual members if the individual algorithms are doing better than random gue...