Raised intracranial pressure (ICP) is associated with poor outcome after brain injury, but is difficult to detect without invasive devices. As a part of the central nervous system, the optic nerve is surrounded by a dural sheath, and the subarachnoid space surrounding the optic nerve is subject to the same pressure changes as the intracranial compartment. Distension of the optic nerve sheath re...

Increased intracranial pressure is suspected in the pathogenesis of acute mountain sickness (AMS), but no studies have correlated it with the presence or severity of AMS. We sought to determine whether increased optic nerve sheath diameter, a surrogate measure of intracranial pressure, is associated with the presence and severity of AMS. We performed a cross-sectional study of travelers ascendi...

Background: During the past decades, surgical intervention is the primary treatment modality for fronto-orbital fibrous dysplasia involving optic nerve. However, controversy has surrounded the role of intra-canal decompression in a number of ways. Objective: Our philosophy of saving optic nerve is that treatment paradigms should be tailored to the individual. Herein, we describe three patients ...

OBJECTIVE To determine whether magnetic resonance (MR) imaging can be used to predict the presence of elevated intracranial pressure. DESIGN Retrospective case series. PARTICIPANTS Twenty patients with pseudotumor cerebri and 20 control subjects. INTERVENTION Magnetic resonance imaging. MAIN OUTCOME MEASURES The presence or absence of the following six neuroimaging signs was measured: (...

Purpose To use finite element (FE) analysis to predict the optic nerve sheath traction forces that act on the optic nerve head (ONH) following horizontal eye movements, and the resulting stress levels in the peripapillary connective tissues of the ONH (Bruch's membrane [BM] and sclera). Methods An FE model of a healthy eye was reconstructed in primary gaze position that included details from ...