S tud en t body p re s id e n t L iz B row n warned student senators Wednesday that unru ly off-campus behavior by students th is weekend could jeopard ize ongoing d iscussions betw een s tu de n t and c ity leaders about the proposed ord inance addressing large parties in South Bend. “ Many o f us have the mentality that by moving o ff campus we are automatically free from the rules and regula...

Thermal denaturation of RNA free coat proteins of tobacco mosaic virus (TMV) was studied for wildtype TMV (vulgare) and the temperature-sensitive mutant, Ni 118. The ability to form soluble aggregates as well as the optical properties (ORD, UV-difference spectra), and the sedimen­ tation behavior were used as criteria for the native state. At pH 7.5 , 7 = 0 .0 2 denaturation is reversible for b...

BACKGROUND Major injuries and death in accidents have roots in drowsiness. Sleepiness is a main result of insufficient sleep. It is vital to explore drowsiness and its level. There are various sorts of methods in the forms of subjective and objective approaches. The goal of this study was to detect the association of subjective and interpretive drowsiness with facial dynamic changes. METHODS ...

Assembly of the synaptonemal complex (SC) in Drosophila depends on two independent pathways defined by the chromosome axis proteins C(2)M and ORD. Because C(2)M encodes a Kleisin-like protein and ORD is required for sister-chromatid cohesion, we tested the hypothesis that these two SC assembly pathways depend on two cohesin complexes. Through single- and double-mutant analysis to study the mito...

Many data stru tures give away mu h more information than they were intended to. Whenever priva y is important, we need to be on erned that it might be possible to infer information from the memory representation of a data stru ture that is not available through its \legitimate" interfa e. Word pro essors that quietly maintain old versions of a do ument are merely the most egregious example of ...

Biomarkers for active tuberculosis (TB) are urgently needed to improve rapid TB diagnosis. The objective of this study was to identify serum protein expression changes associated with TB but not latent Mycobacterium tuberculosis infection (LTBI), uninfected states, or respiratory diseases other than TB (ORD). Serum samples from 209 HIV uninfected (HIV(-)) and co-infected (HIV(+)) individuals we...

A primary feature of age-related macular degeneration (AMD) is the presence of extracellular deposits between the retinal pigment epithelium (RPE) and underlying Bruch's membrane, leading to RPE dysfunction, photoreceptor death and severe visual loss. AMD accounts for about 50% of blind registrations in Western countries and is a common, genetically complex disorder. Very little is known regard...

Normally, meiotic crossovers in conjunction with sister-chromatid cohesion establish a physical connection between homologs that is required for their accurate segregation during the first meiotic division. However, in some organisms an alternative mechanism ensures the proper segregation of bivalents that fail to recombine. In Drosophila oocytes, accurate segregation of achiasmate homologs dep...