Residential proximity to applications of agricultural pesticides may be an important source of exposure to agents that have been classified as developmental toxins. Data on two case-control study populations of infants with neural tube defects (NTDs) and nonmalformed controls delivered in California between 1987 and 1991 were pooled to investigate whether maternal residential proximity to appli...

Nineteen representative water samples were collected from surface and ground water sources, covering urban, rural area, shallow and deep aquifers in Pondicherry region. The samples were analysed for various pesticide residues such as HCH, Aldrin and DDT. Both surface and ground water sources found to exhibit the residuals of various pesticides. The residual levels oforganochlorine pesticides we...

The purpose of this study was to investigate the nuclear magnetic resonance (NMR) assignments of hydrolyzed products extracted from human blood plasma. The correlations between chemical, functional and structural properties of highly toxic pesticides were investigated using the PreADME analysis. We observed that toxic pesticides possessed higher molecular weight and, more hydrogen bond donors a...

The deficiencies associated with current risk assessment and negligible risk methodologies used to protect public health and the environment during the current epidemic of environmentally induced diseases serve as the imperative for moving ahead with a program to phase out hazardous pesticides and to implement alternatives. With the release of the National Academy of Sciences June 1993 report, ...

OBJECTIVE Circumstantial evidence suggests that organic farmers may have higher sperm count than other men, but comprehensive epidemiological studies of male fecundity among farmers have never been carried out. A substantial increase of sperm count is expected to translate into a shorter time to pregnancy--the number of menstrual cycles or months it takes a couple to get pregnant from discontin...

Micronucleus (MN) is a biomarker widely used in biomonitoring studies carried out to determine the genetic risk associated to pesticide exposure. Many in vitro and in vivo studies, as well as epidemiological approaches, have demonstrated the ability of certain chemical pesticides to produce genetic effects including cancer and other chronic pathologies in humans; thus, biomonitoring studies hav...

Commercialization of horticulture farming, expansion of farms, and the practice of monoculture favor the proliferation of pests, which in turn increases the need for pesticides. Increased exposure to pesticides is associated with inadequate knowledge on the hazardous nature of pesticides, poor hygiene practices, lack of availability of washing facilities, and insufficient adherence to precautio...

A multi-residue method for 122 pesticides in agricultural products was validated in accordance with Japanese guidelines for residual agricultural chemicals in food. The sample was extracted with acetonitrile. Co-extractives were removed by GPC-graphitized carbon column SPE, followed by silica gel/PSA cartridge column SPE. The pesticides in the test solution were determined by LC-MS/MS using sch...

Pesticides have been suspected to act as endocrine disruptive compounds (EDCs) through several mechanisms of action, however data are still needed for a number of currently used pesticides. In the present study, 30 environmental pesticides selected from different chemical classes (azole, carbamate, dicarboximide, organochlorine, organophosphorus, oxadiazole, phenylureas, pyrazole, pyrimidine, p...

Pesticides are commonly used worldwide both in agricultural and domestic settings. The benefits to society and agriculture are well documented. There are, however, dangers associated with the use of pesticides. Some pesticides, such as organophosphates (the most commonly used pesticide worldwide), kill pests through a biological pathway that may also cause harm to humans. Acute exposure to pest...