It is recognized that scatter correction can supply more accurate absolute quantification, and that iterative reconstruction results in better noise properties and significantly reduces streak artefacts; however, it is not entirely clear whether they produce significant changes in [18F]-FDG distribution of reconstructed 3D brain PET images relative to not scatter corrected images and analytic r...

BACKGROUND In integrated PET/MR hybrid imaging the evaluation of PET performance characteristics according to the NEMA standard NU 2-2007 is challenging because of incomplete MR-based attenuation correction (AC) for phantom imaging. In this study, a strategy for CT-based AC of the NEMA image quality (IQ) phantom is assessed. The method is systematically evaluated in NEMA IQ phantom measurements...

We report on the NEMA-NU2-2012 performance of a hypothetical Monte Carlo (MC) model, Ex-PET, Siemens Biograph Vision positron emission tomography (PET)/CT (Bio-Vis) with sparse detector module rings and extended axial field view (AFOV). MC simulations were performed interleaved 32-mm gaps, equivalent to dimension each module, yielding an AFOV 48.0 cm (Bio-Vis has 25.6-cm AFOV). 3D-PET acquisiti...

INSERM UMR1101, LaTIM, Brest, France Respiratory motion in PET/MR imaging leads to reduced quantitative and qualitative image accuracy. Correction methodologies include the use of respiratory synchronized gated frames which lead to low signal to noise ratio (SNR) given that each frame contains only part of the count available throughout an average PET acquisition. In this work, 4D MRI extracted...

Introduction: Although left ventricular(LV) function parameters measured by gated myocardial perfusion SPECT (GSPECT) have been validated, experimental data have revealed that the calculated the LV function parameters using GSPECT are affected by patient populations as well as particular acquisition and processing conditions. We tried to determine the normal values of GSPECT in an Iranian popul...

The aim of this work is to support the better quantification of Positron Emission Tomography (PET) images on the basis of associated structural information. This would involve an addressal of the Partial Volume Effect (PVE) [1], which basically demands better resolution data. To this end, one approach is to apply image space correction techniques that adjust the data on the basis of compartment...

BACKGROUND The amount of inhomogeneities in a (99m)Tc Technegas single-photon emission computed tomography (SPECT) lung image, caused by reduced ventilation in lung regions affected by chronic obstructive pulmonary disease (COPD), is correlated to disease advancement. A quantitative analysis method, the CVT method, measuring these inhomogeneities was proposed in earlier work. To detect mild COP...

A 4D ordered-subsets maximum a posteriori (OSMAP) algorithm for dynamic SPECT is described which uses a temporal prior that constrains each voxel's behaviour in time to conform to a compartmental model. No a priori limitations on kinetic parameters are applied; rather, the parameter estimates evolve as the algorithm iterates to a solution. The estimated parameters and time-activity curves are u...