OBJECTIVE To evaluate bone mineral density and biochemical parameters of bone metabolism in ambulatory premenopausal female patients with systemic lupus erythematosus (SLE). METHODS 30 women who fulfilled the ARA criteria for the classification of SLE were studied. Lumbar and femoral bone mineral density was determined by dual energy x ray absorptiometry. Various laboratory parameters includi...

BACKGROUND A high prevalence of osteopenia and osteoporosis is observed in patients with inflammatory bowel disease (IBD). Various risk factors of bone loss have been suggested in IBD. The aim of the present study was to investigate the prevalence of low bone mineral density (BMD) and to identify related risk factors in Greek patients with IBD. METHODS One hundred and eighteen consecutive IBD...

OBJECTIVE To determine the association between insulin growth factor 1 (IGF-1) and bone mineral density (BMD) in men over 65 years of age. SUBJECTS AND METHODS Forty-one male patients aged 65-88 years without a history of drug use or illness which is known to affect BMD were enrolled in the study. The control group consisted of 20 healthy men (19-62 years old). An immunoradiometric assay was ...

OBJECTIVE The purpose of this study is to investigate the incidence of new compression and to analyze factors that influence the fractures in adjacent levels after percutaneous vertebroplasty (PVP). METHODS This retrospective study examined 206 patients who had undergone PVP for single level osteoporotic or osteopenic compression fractures during the last seven years in our department. After ...

BACKGROUND The results of previous studies on the association between blood mercury (Hg) and bone mineral density (BMD) are inconsistent. We therefore used a large-scale nationwide representative sample of Korean men to investigate the relationship between these two parameters. METHODS A nationwide cross-sectional study was conducted using data from the 2008 to 2010 Korean National Health and...

Purpose of the study. To study calcium-phosphorus metabolism in patients with peptic ulcer (PU) comparison bone mineral density (BMD), its age and gender aspects. Materials methods. 216 people were remission 154 without history erosive-ulcerative changes during fibrogastroduodenoscopy (FGDS) examined. All underwent clinical endoscopic studies, dichromatic X-ray densitometry calculation T-test f...

BACKGROUND Subchondral osteopenia is important for the pathophysiology of osteoarthritis (OA). Although previous studies suggest that plasminogen activator inhibitor-1 (PAI-1), an inhibitor of fibrinolysis, is related to bone metabolism, its role in OA remains unknown. We therefore investigated the roles of PAI-1 in the subchondral bone in OA model mice. METHODS Wild type (WT) and PAI-1-defic...

OBJECTIVE/HYPOTHESIS Idiopathic benign paroxysmal positional vertigo (BPPV) is a strong indicator of decreased bone density (osteopenia/osteoporosis) in postmenopausal women, and there is a correlation between BPPV and serum levels of biochemical markers of bone turnover. STUDY DESIGN Prospective pilot clinical trial. METHODS Two groups of postmenopausal women were recruited. The BPPV group...

[Purpose] This study investigated the effect of the Weight-bearing Exercise for Better Balance program on the strength of hip flexors, extensors, abductors, adductors, and knee flexors and extensors and balance in osteopenia. [Subjects and Methods] Twenty-four postmenopausal females with osteopenia volunteered to participate in this study and were randomly assigned into two equal groups of 12: ...

OBJECTIVE This study aimed to assess the association between bone mineral density (BMD) and coronary atherosclerosis in healthy postmenopausal women. METHODS We performed a retrospective review of 252 postmenopausal women who had visited a health promotion center for a routine checkup. BMD of the lumbar spine (L1-L4) and femoral neck was evaluated using dual-energy X-ray absorptiometry, and c...