Many chemicals in the environment, especially those with estrogenic activity, are able to disrupt the programming of endocrine signaling pathways established during development; these chemicals are referred to as endocrine-disrupting chemicals. Altered programming can result in numerous adverse consequences in estrogen-target tissues, some of which may not be apparent until later in life. For e...

This paper presents the toxicity data of 10 nonpolar narcotic chemicals on Pseudokirchneriella subcapitata (green algae) assessed by a new algal toxicity testing technique conducted under air-tight environment. Based on DO production, median effective concentration (EC50) varies from 1.73 mg/L (1-octanol) to 8,040 mg/L (2-propanol). The endpoint of algal growth rate reveals similar sensitivity ...

Many thousands of chemicals are produced industrially and many more occur naturally. Information on the toxicology of these chemicals is often minimal or absent. The International Agency for Research on Cancer (IARC) has published evaluations of the carcinogenic risk to humans of over 700 chemicals, groups of chemicals, and complex mixtures as a regular series of monographs. A database has been...

489 C o m m e n t a r y Our bodies and our surroundings contain an enormous array of chemicals. Although many of these chemicals are useful and even essential for survival, others are potentially harmful. A challenge all animals face is to sense which chemicals are useful and which are harmful. Considered in the context of feeding behavior, this challenge is highly asymmetric. Although animals ...

although, grapevines do not have a high chilling requirement, its fulfillment is critical for normal development of the vines. in tropical and subtropical regions such as farrashband, in the south of iran, there is no adequate winter chilling to release bud dormancy in grapevines. so it is necessary to consider the effect of chemical dormancy–breaking agents on bud dormancy. in the present rese...

Chemicals, including inorganic chemicals (nanoparticles, heavy metals, and other chemicals) and organic chemicals (pesticides, POPS, PBDEs, and other organic chemicals), are widely used in the world in recent 30 years to support the rapid development of industrialization and agriculture. The extensive use and discharge of these chemicals in these processes will produce wastewater containing a v...

0199 Epidemics of overt toxicity following widespread environmental contamination from commercial toxins heralded the discovery of children’s enhanced vulnerability to lead, methyl mercury, polychlorinated biphenyls (PCBs), and tobacco [1,2,3,4,5] (Box 1). Over the past three decades, researchers have found that remarkably low-level exposures to these toxins are linked with less overt symptoms ...

Over the past 3 decades, in a series of studies on some of the most extensively studied toxic chemicals and pollutants, scientists have found that the amount of toxic chemical linked with the development of a disease or death-which is central to determining "safe" or "hazardous" levels-is proportionately greater at the lowest dose or levels of exposure. These results, which are contrary to the ...