BACKGROUND AND PURPOSE Hand warming and face warming, combined with inhalation of heated air, are reported to suppress shivering. However, hand or face temperature contributes only a few percent to control of shivering. Thus, it seems unlikely that manipulating hand or facial skin temperature alone would be sufficient to permit induction of therapeutic hypothermia. We tested the hypothesis that...

OBJECTIVE To determine the impact of counter warming (CW) with an air circulating blanket on shivering and metabolic profile during therapeutic temperature modulation (TTM). DESIGN A prospective observational study. SETTING An 18-bed neurologic intensive care unit. PATIENTS Fifty mechanically ventilated patients with brain injury undergoing TTM with automated surface and intravascular dev...

Three patients who had suffered episodes of spontaneous hypothermia are described. Circulatory control was normal for their age but there was evidence of a persistent defect of thermoregulatory mechanisms. In all patients vascular thermoregulatory reflexes dependent upon peripheral receptors were active and in two patients reflex shivering could be obtained. There appeared, however, to be a fai...

Dear Editor, Shivering happens frequently in 5 to 60% of surgical operations. 1 Though it occurs as a result of temperature reduction, it may occur in patients with a post-operative normal body temperature. 2 Shivering may be dangerous due to increasing effect of medicines, extension of recovery period, increased oxygen consumption or hemostatic dysfunction especially in patients with a low car...

Body temperature homoeostasis in mammals is governed centrally through the regulation of shivering and non-shivering thermogenesis and cutaneous vasomotion. Non-shivering thermogenesis in brown adipose tissue (BAT) is mediated by sympathetic activation, followed by PGC-1α induction, which drives UCP1. Here we identify nardilysin (Nrd1 and NRDc) as a critical regulator of body temperature homoeo...

Shivering is the only universal facultative thermogenic mechanism in endothermic vertebrates. Skeletal muscle constitutes a large proportion of body mass and a high scope of metabolic rate, and thus heat production, between resting level and active contraction. Its contractile activity is under rapid and accurate neural control. Together with the inherently low metabolic efficiency of muscle, t...

Mammals and birds are endotherms and respond to cold exposure by the means of regulatory thermogenesis, either shivering or non-shivering. In this latter case, waste of cell energy as heat can be achieved by uncoupling of mitochondrial respiration. Uncoupling proteins, which belong to the mitochondrial carrier family, are able to transport protons and thus may assume a thermogenic function. The...

KMEN, AaaoT-r T., CLIFFORD B. REIFLER, AND VIcroR H. shivering. The predominant role oi the peripheral mecha"THALV2. Modification of thermoregulatory response to cold by hypnosis. nism in the initiation of shivering has been stressed by J. Appl. Physiol. i9(6): 1o43-1050. i9 64 .-The effects of Lim (27). Helmendach and Meehan (16) noted that the hypnosis on thermoregulatory responses were studi...