A series of glycan-coated quantum dots were prepared to probe the effect of glycan presentation in intracellular localization in HeLa and SV40 epithelial cells. We show that glycan density mostly impacts on cell toxicity, whereas glycan type affects the cell uptake and intracellular localization. Moreover, we show that lactose can act as a "Trojan horse" on bi-functionalized QDs to help intrace...

Much literature examines the relationship between the spatial availability of alcohol and alcohol-related harm. This study aims to address an important gap in this evidence by using detailed outlet data to examine recent temporal trends in the sociodemographic distribution of spatial availability for different types of alcohol outlet in England. Descriptive analysis of measures of alcohol outle...

513 COVER A jumble of icebergs forms in front of the heavily crevassed calving front of Jakobshavn Isbrae, one of the fastest outlet glaciers draining the Greenland Ice Sheet. The ~5-kilometer-wide ice front rises ~80 meters out of the water and extends more than 600 meters underwater. Recent research shows that the speeds of Greenland glaciers are increasing. See page 576.

Organic fluids could be classified into wet, dry and isentropic types according to the slope of the saturated vapor envelope on a temperature-entropy diagram. Due to the limited availability of pure isentropic refrigerants, attempts are made to make isentropic mixtures by mixing wet and dry refrigerants with an appropriate composition in the present work. A simple principle for selecting potent...

The present study investigated the effect of operating parameters of a laboratory spray dryer on powder characteristics, in order to optimise the production of trehalose and raffinose powders, intended to be used as carriers of biomolecules for inhalation. The sugars were spray dried from 80:20 methanol:n-butyl acetate (v/v) solutions using a Büchi Mini Spray dryer B-290. A 2(4) factorial desig...

In this study, a three dimensional (3D) modeling has been built for a lithium ion battery pack using the field synergy principle to obtain a better thermal distribution. In the model, the thermal behavior of the battery pack was studied by reducing the maximum temperature, improving the temperature uniformity and considering the difference between the maximum and maximum temperature of the batt...

Abstract High Temperature Gas-cooled Reactor (HTGR), which has well-known safety features and high temperature heat supply capability, is expected to be widely used for technology utilization including the hydrogen production, so contributing reduction of carbon dioxide emissions in various sectors. The 10 MW gas-cooled test (HTR-10) had been constructed operated China as a pilot plant demonstr...

To provide a favorable temperature for power battery liquid cooling system, bionic blood vessel structure of the plate is designed based on knowledge bionics and human model. For three different discharge rates 1C, 2C, 3C, FLUENT used to simulate analyze heat dissipation performance with vascular structure. The influence pipe distance (A1 A2) at coolant outlet, thickness plate, inner turning ra...

In this research, a water-water heat pump system using waste water as a heat source, a type that is not often used in Turkey and the World, was experimentally modeled. The experiments were performed under the conditions of simulated waste water temperature values of 20 °C, 30 °C and 40 °C. Inlet and outlet water temperatures of the evaporator and condenser, water flow rates in the evaporator an...