To evaluate a possible role for colony stimulating factor-1 (CSF-1) in human ovarian function, the peripheral blood CSF-1 concentration throughout the human menstrual cycle and during ovarian stimulation was monitored. Blood was sampled across the menstrual cycle (n = 10) and at specific times during ovarian stimulation. In addition, the CSF-1 concentrations in follicular fluid (FF) during the ...

Background: Ovarian reserve and ovarian response both are of the most important key factors in infertility treatment. Anti mullerian hormone (AMH) is one of lab tests that can predict ovarian reserve. relation between this assay and ovarian response can guide physition to choose the best protocol for the worst reserve. Materials and Methods: In a prospective cohort study, 110 infertile women (2...

background: controlled ovarian hyper stimulation coh/iui represents a therapy applicable to a wide variety of infertility diagnosis with no significant mechanical distortion of pelvic viscera. identified variables influenced in intra uterine insemination include: age, cause of infertility, sperm number, motility and normal percentage, use of gonadotropine and number of attempts at iui. the role...

STUDY QUESTION Can controlled ovarian stimulation with low-dose human menopausal gonadotrophin (hMG) improve the clinical pregnancy rate when compared with ovarian stimulation with clomiphene citrate (CC) in an intrauterine insemination (IUI) programme for subfertile couples? SUMMARY ANSWER Ovarian stimulation with low-dose hMG is superior to CC in IUI cycles with respect to clinical pregnanc...

It is known that the follicular selection and final stages of follicular maturation are equal if not more dependent on low circulating levels of LH.In addition to stimulating production of thecal androgens as substrate for estrogen synthesis, LH stimulates granulose cell via LH receptors induced by FSH and estrogen in larger but not smaller follicles. The data from numerous assisted reproductio...

High-resolution array comparative genomic hybridization of 235 serous epithelial ovarian cancers demonstrated a regional increase at 3q26.2 encompassing SnoN/SkiL, a coregulator of SMAD/TGFbeta signaling. SnoN RNA transcripts were elevated in approximately 80% of advanced stage serous epithelial ovarian cancers. In both immortalized normal (TIOSE) and ovarian carcinoma cell lines (OVCA), SnoN R...