نتایج جستجو برای: ovarian transplantation
تعداد نتایج: 224946 فیلتر نتایج به سال:
We describe a patient with primary ovarian carcinoma that developed after liver transplantation whose tumor was highly positive for prostatespecific antigen (PSA). PSA in tumor tissue was characterized by two immunoassays, HPLC, immunohistochemistry, reverse transcriptionPCR, Southern blotting, and DNA sequencing. PSA in the ovarian tumor was present as free, M, 33,000 protein (>90%) and as PSA...
In this issue, Dr Tilly’s laboratory presents another challenge to a half century– old dogma that ovarian reserve, made up of primordial follicles, cannot be replenished after birth. Their earlier work indicated that egg manufacturing continued into adult life in mice and that germ stem cells could have originated from the bone marrow; this work was met with much skepticism. It has been known f...
Although multiple follicles are present in mammalian ovaries, most of them remain dormant for years or decades. During reproductive life, some follicles are activated for development. Genetically modified mouse models with oocyte-specific deletion of genes in the PTEN-PI3K-Akt-Foxo3 pathway exhibited premature activation of all dormant follicles. Using an inhibitor of the Phosphatase with TENsi...
BACKGROUND AND OBJECTIVE Establishing ovarian cancer cell lines will benefit researches on biological characteristics of ovarian cancer stem cells and antitumor drugs. This study was to establish a human ovarian carcinoma cell line from peritoneal effusion, and explore its biological characteristics. METHODS Cells were isolated from peritoneal effusion of an ovarian carcinoma patient, purifie...
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