Around 1.5% of adults in Europe and the USA have urge urinary incontinence (involuntary leakage immediately preceded or accompanied by urgency) (Abrams 2003; Irwin 2006). This is usually due to overactive bladder syndrome (defined as urgency, with or without urge incontinence, and usually with frequency and nocturia) (Abrams 2003). The symptoms of an overactive bladder are thought to be due to ...

• Objective: To review the diagnosis and treatment of overactive bladder (OAB). • Methods: Qualitative assessment of the literature. • Results: OAB syndrome is a highly prevalent disorder that remains vastly underreported. Typical symptoms include urinary frequency, urinary urgency, and urinary urge incontinence. Symptoms can be disruptive and impair quality of life. Behavioral therapy is the c...

OBJECTIVES To determine whether there are differences in pressure and flow measurements between conventional cystometry (CONV) and ambulatory urodynamic monitoring (AMB) in women with overactive bladder syndrome and urinary incontinence. MATERIALS AND METHODS Retrospective study which included female subjects who underwent both CONV (with saline filling medium) and AMB, separated by less than...

Currently, the most widely used and effective pharmacologic treatment for the overactive bladder (OAB) is administration of muscarinic receptor antagonists. This strongly suggests that acetylcholine plays some role in the aetiology of bladder overactivity. If one considers the classical picture of the involvement of acetylcholine in the human bladder, this seems surprising. Acetylcholine is the...

Several physiopathologic conditions lead to the manifestation of overactive bladder (OAB). These conditions include ageing, diabetes mellitus, bladder outlet obstruction, spinal cord injury, stroke and brain injury, Parkinson's disease, multiple sclerosis, interstitial cystitis, stress and depression. This review has discussed research findings in human and animal studies conducted on the above...