PrP(C), the cellular isoform of prion protein, is widely expressed in most tissues. Despite its involvement in several bioprocesses it still has no apparent physiological role. During propagation of Transmissible Spongiform Encephalopathies, PrP(C) is converted to the pathological isoform, PrP(Sc), in a process believed to be mediated by unknown host factors. PrP(Sc) has altered biochemical pro...

Irrespective of aetiology, infectious respiratory diseases of sheep and goats contribute to 5.6 percent of the total diseases of small ruminants. These infectious respiratory disorders are divided into two groups: the diseases of upper respiratory tract, namely, nasal myiasis and enzootic nasal tumors, and diseases of lower respiratory tract, namely, peste des petits ruminants (PPR), parainflue...

Paratuberculosis (PTCB) or Johne's disease (JD) caused by a slow growing acid fast bacillus Mycobacterium avium subspecies paratuberculosis (MAP), is an infectious of many species including humans. The responsible for important economic losses to livestock industry worldwide. Although the widespread, it had not been studied in Algerian sheep. In this study we inspected presence infection sheep ...

Members of Artiodactyla can contract the infectious disease Malignant Catarrhal Fever (MCF), which has a wide range symptoms. Ten known viruses contribute to disease, two most significant ones being Ovine gamma herpes virus 2 (OvHV-2) and Alcelaphine 1 (AIHV-1). In African subcontinent, AIHV-1 is seen in MCF cases. Indian scenario, virus-2 main culprit. reported certain pockets India. Its threa...

PURPOSE To produce two-dimensional electrophoresis (2-DE) maps for ovine crystallins and examine changes in ovine crystallins during cataract formation. METHODS Soluble and insoluble fractions were isolated from normal, whole lenses of 26-week-old sheep, the proteins separated by 2-DE, and the spots digested with trypsin and subjected to tandem mass spectral analysis. Spot identifications wer...