Bone loss diseases are often associated with increased receptor activator of NF-κB ligand (RANKL)-induced osteoclast formation. Compounds that can attenuate RANKL-mediated osteoclast formation are of great biomedical interest. Eugenol, a phenolic constituent of clove oil possesses medicinal properties; however, its anti-osteoclastogenic potential is unexplored hitherto. Here, we found that euge...

BACKGROUND This in vitro study was conducted to compare the compression resistance of various interocclusal recording materials when subjected to a compressive load. MATERIALS AND METHODS Each interocclusal recording material was manipulated according to the manufacturer instruction and placed into a metallic cylinder. A total of 20 specimens for each interocclusal recording material were mad...

BACKGROUND Essential oil components eugenol and carvacrol (ranging between 100 and 200 ppm for carvacrol and between 250 and 750 ppm for eugenol) were tested for antifungal activity against foodborne pathogenic fungal species Aspergillus carbonarius A1102 and Penicillium roqueforti PTFKK29 in in vitro and in situ conditions. MATERIALS AND METHODS In vitro antifungal activity of eugenol and ca...

AIM Remnants of provisional cement on the internal surface of cast restorations can have an adverse effect on the performance of the definitive luting agent. The purpose of this study was to evaluate the effect of eugenol-containing temporary cement removal by an ultrasonic or an organic solvent on the retentive strength of metallic rings cemented to amalgam cores using zinc phosphate cement. ...

PURPOSE The purpose of this retrospective study was to assess the success of pulpotomies performed on an emergency basis and restored with a temporary zinc-oxide eugenol restorative material. METHODS Records were collected from 216 pulpotomies in primary molars performed on an emergency basis by pediatric dental residents at the University of Florida pediatric dental clinic between July 1999 ...

Pulpal response of four calcium hydroxide liners, MPC 10, MPC 12, Dycal and Pulpdent were tested on primary and permanent teeth with zinc oxide and eugenol (ZOE) and silicate as controls. Responses of the pulps were evaluatedi in Rhesus monkeys, utilizing Class V cavity preparations at 3 days, 5 and 8 weeks. An equivalent number of anterior and posterior teeth were studied for all compounds. Th...

Plant extracts, or phytonutrients, are used in traditional medicine practices as supplements to enhance the immune system and gain resistance to various infectious diseases and are used in animal production as health promoting feed additives. To date, there are no studies that have assessed their mechanism of action and ability to alter mucosal immune responses in the intestine. We characterize...

We evaluated the acute toxicities and the physiological effects of plant monoterpenoids (eugenol, pulegone, citronellal and alpha-terpineol) and neuroactive insecticides (malathion, dieldrin and RH3421) on flight muscle impulses (FMI) and wing beat signals (WBS) of the blow fly (Phaenicia sericata). Topically-applied eugenol, pulegone, citronellal, and alpha-terpineol produced neurotoxic sympto...

Eugenol, the active principle of clove oil is a potent antioxidant and a well known anti-inflammatory agent. In an earlier study, we have reported the in vitro inhibition of human platelet aggregation and LTC4 formation in rat PMNL cells. In the present study, an attempt has been made to monitor the in vivo and in vitro modulation of platelet aggregation and eicosanoids (TXB2, LTC4) by eugenol ...

AIM To determine how eugenol affects fermentation parameters and faecal coliforms in cattle and swine waste slurries stored anaerobically. METHODS AND RESULTS Waste slurries (faeces:urine:water, 50:35:15) were blended with and without additives and aliquoted to triplicate 1-l flasks. Faecal coliforms were eliminated in cattle and swine waste slurries within 1 or 2 days with additions of eugen...