A novel class of water-soluble iron nitrosyl complexes has been developed for use as NO donor prodrugs. To elaborate these NO prodrugs various water-soluble ligands were used such as P(CH2OH)3, 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane (PTA), 1,2-bis[bis(hydroxymethyl)phosphino]ethane (HMPE), 1,2-bis[bis(hydroxymethyl)phosphino]benzene (TMBz), cysteamine, cysteamine hydrochloride, L-cystein...

The title compound, [Fe(2)(C(9)H(11)NS(2)){Fe(C(5)H(5))(C(17)H(14)P)}(CO)(5)], was prepared as an aza-dithiol-ato-iron model for the iron-only hydrogenase active site. The Fe(2)S(2) unit exhibits a butterfly conformation and the ferrocenyldiphenyl-phosphine ligand is trans to the Fe-Fe bond. The Fe-Fe distance of 2.5160 (8) Å is longer than found in related model structures. Intra-molecular C-H...

Iron supplementation may have adverse health effects in infants, probably through manipulation of the gut microbiome. Previous research in low-resource settings have focused primarily on anemic infants. This was a double blind, randomized, controlled trial of home fortification comparing multiple micronutrient powder (MNP) with and without iron. Six-month-old, non- or mildly anemic, predominant...

Recent updates on phase relations of Earth’s core-forming materials, Fe alloys, as a function pressure (P), temperature (T), and composition (X) are reviewed for the Fe, Fe-Ni, Fe-O, Fe-Si, Fe-S, Fe-C, Fe-H, Fe-Ni-Si, Fe-Si-O systems. Thermodynamic models these systems highlighted where available, starting with 1 bar to high-P-T conditions. For binary systems, longitudinal wave velocity density...

A collection of 155 accessions of ancient Portuguese common beans (Phaseolus vulgaris L.) was evaluated in relation to the content of 8 minerals (Zn, Cu, Fe, Mn, Ca, Mg, P and K) important for human nutrition. A high degree of variability for P, Fe, Zn, Cu, Mn and Ca was observed in the collection. Total correlation matrix analysis revealed the existence of two important sets of strong positive...

Vivianite (Fe3(PO4)2?8H2O) is a potential phosphorus (P) recovery product from wastewater treatment plants (WWTPs). However, routine methods for quantification of vivianite bound P (vivianite-P) are needed to establish the link between formation and operating conditions, as current approaches require specialized instrumentation (Mössbauer or synchrotron). This study modified conventional sequen...

As feed represents 60 to 70% of the cost of raising an animal to market weight, feed efficiency (the amount of dry weight intake to amount of wet weight gain) remains an important genetic trait in animal agriculture. To gain greater understanding of cellular mechanisms of feed efficiency (FE), shotgun proteomics was conducted using in-gel trypsin digestion and tandem mass spectrometry on breast...

The current study was conducted to investigate the effects of dietary iron-loaded chitooligosacharide nanoparticles (Fe-CNP) on occurrence of bacterial chondronecrosis with osteomyelitis (BCO) in broiler chickens. Four hundred eighty day-old chicks (Ross 308) were assigned to four treatments with six replicates of 20 birds. All chicks were reared on wire flooring system up to 42 days of age. Th...

Gallium (Ga) is a semimetallic element that has demonstrated therapeutic and diagnostic-imaging potential in a number of disease settings, including cancer and infectious diseases. Gallium's biological actions stem from its ionic radius being almost the same as that of ferric iron (Fe(3+)), whereby it can replace iron (Fe) in Fe(3+)-dependent biological systems, such as bacterial and mammalian ...