Background: The root cortex of Paeonia suffruticosa Andrews (Paeoniaceae), which is also called moutan bark, known as Botanpi in Japan. This crude drug has been used several Kampo formulas, such Daiobotanpito, to treat menstrual disturbance and constipation by improving blood stasis suppressing inflammation. However, the anti-inflammatory effect not well studied.Objective: To clarify effects we...