نتایج جستجو برای: pantothenate kinase
تعداد نتایج: 227686 فیلتر نتایج به سال:
1. Research School of Biology, The Australian National University, Canberra, Australia 2. Department of Chemistry, University of Glasgow, Glasgow, United Kingdom 3. Department of Chemistry, McGill University, Montreal, Quebec, Canada 4. Department of Biochemistry, Stellenbosch University, Matieland, South Africa 5. Monash Institute of Pharmaceutical Sciences, Monash University, Melbourne, Austr...
Toll-like receptors (TLRs) modulate the expression of multiple microRNAs (miRNAs). Here, we report the down-regulation of miR-107 by TLR4 in multiple cell types. The miR-107 sequence occurs in an intron within the sequence encoding the gene for pantothenate kinase 1α (PanK1α), which is regulated by the transcription factor peroxisome proliferator-activating receptor α (PPAR-α). PanK1α is also d...
During the course of experimental work on acquired hypotrichosis and canities, it was noted that in discoid lupus erythematosus of the scalp there was improvement of the inflammatory phase of the disease associated with calcium pantothenate therapy. Following this, a series of patients with subacute and localized and disseminated discoid lupus crythematosus was studied with oral calcium pantoth...
Mutants lacking the first enzyme in de novo purine synthesis (PurF) can synthesize thiamine if increased levels of pantothenate are present in the culture medium (J. L. Enos-Berlage and D. M. Downs, J. Bacteriol. 178:1476-1479, 1996). Derivatives of purF mutants that no longer required pantothenate for thiamine-independent growth were isolated. Analysis of these mutants demonstrated that they w...
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