Sir, Cutaneous involvement in adults infected with human herpes virus 6 (HHV-6) is rare. Exanthematous reactions in immunosuppressed transplant patients and 1 case of reactive haemophagocytic syndrome have been reported (1, 2). Recently we described a case of erythema elevatum diutinum, a rare form of chronic cutaneous vasculitis, envisaging the aetiological role of HHV-6 (3). We describe here ...

Background: C3 glomerulopathy (C3GP) including dense deposit disease (DDD) is mediated by abnormal activation of the alternative complement pathway (ACP). In children and young adults, mutations of complement or complement regulatory proteins are the major causative factors but in adults there appears to be an increased incidence of monoclonal gammopathy and it has been proposed that the parapr...

The 1983 article entitled “Chronic lymphocytic leukemia and other chronic lymphoid proliferations: surface marker phenotypes and clinical correlations,” which is reprinted in this issue of the Journal of Clinical Oncology, was one of the first reporting the use of monoclonal antibodies to expand the phenotypic characterization of chronic lymphoid leukemia, and one of the earliest to examine cli...

Copyright © 2014, Nephrology and Urology Research Center; Published by Kowsar Corp. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Dear Editor, The hemolytic-uremic syndrome (HUS) is a serious disorder of microangiop...

To determine whether primary lymph node plasmacytoma (PLNP) is a distinct entity among other types of plasma cell neoplasia, we analyzed a large series of PLNPs from 2 large lymphoma registries to compare histologic, immunophenotypic, and clinical features of PLNPs, nonnodal extramedullary plasmacytomas, and multiple myeloma. Twenty-five PLNPs (clinical data on 15 cases) were compared with 10 n...