The background and current context of work on the shikimate-pathway enzymes as potential targets for anti-bacterial, anti-fungal and anti-parasitic drugs is reviewed. Recent work on the third enzyme of the pathway, dehydroquinase, which occurs in two structurally and mechanistically distinct forms, is used to illustrate the present state of studies into rational drug design.

13 watt Current Mode Class-D (CMCD) with 60% efficiency is presented. This amplifier is the highest power switch mode microwave power amplifier reported to date. The CMCD architecture is an improvement over the Voltage Mode Class-D in that the parasitic reactance in the active device can be absorbed into the tank circuit resulting in a zero voltage switching condition.

Hydatid cyst is a parasitic disease caused by infection with Taenia echinococcus that is endemic to many areas of the world, but due to the current ease of worldwide travel may be seen also in non-endemic areas. The disease commonly affects the liver and the lungs, but may also involve the central nervous system (CNS).

The paper presents the method of increasing the speed of sensors with high output resistance, for example, photodiode of optical systems for transmitting digital information. The features of method of correcting circuit of current-voltage converters, which compensate the influence of parasitic capacitance of sensor on its bandwidth and the settling time of the transient process are considered.

A brief review of the main physical results about the low temperature characterization and modeIing of Si CMOS devices is presented. More specifically, the carrier mobility law. the saturation velocity, the short channel effects, the impact ionization phenomenon. the hot carrier effects or the parasitic leakage current are physically discussed.

AbspuctThe saturable inductor is employed in the fullbridge (FB) zero-voltage-switched (ZVS) pulsewidth-modulated (PWM) converter to improve its performance. The current and voltage stresses of the switches as well as parasitic oscillations are significantly reduced compared to those of the conventional FBZVS-PWM converter. The qualitative analysis is presented and is verified on a 500 KHz, 5 V...

Phoradendron, the largest mistletoe genus in the New World, extends from temperate North America to temperate South America. Most species are parasitic on terrestrial hosts, but a few occur only, or primarily, on other species of Phoradendron. We examined relationships among two obligate epiparasites, P. durangense and P. falcatum, and their parasitic hosts. Fruit and seed of both epiparasites ...

The presented high-voltage DC source was designed to enable laboratory measurements of reverse and forward characteristics in non-conducting state of power semiconductor components. It also enables to measure the minimum triggering current or control voltage in dependence of the voltage on main electrodes for SCR, triac or voltage-controlled semiconductor devices such as MOSFET and IGBT, respec...