P * PChairman, Bihar State Environment Impact Assessment Authority, Govt. of India & Corresponding Author 1. Abstract: Signal transduction by xenobiotics in fish has gained much attention in the recent decade. Organophosphates and carbamates bind specifically to the membrane bound enzyme acetylcholinesterase affecting neural transmission. Since nervous system is one of the important physiologic...

A bacterial strain C5 that can produce new type of marine esterase was isolated and screened from marine sludge. According to 16S rRNA sequence analysis and physiological and biochemical experiments, the strain was identified as Bacillus subtilis. A single isozyme with a molecular weight of 86 kDa was observed by SDS-PAGE and native-PAGE. On this basis, the mechanism of esterase B1 secreted by ...

A degradative bacterium, M6, was isolated and presumptively identified as Plesiomonas sp. strain M6 was able to hydrolyze methyl parathion to p-nitrophenol. A novel organophosphate hydrolase gene designated mpd was selected from its genomic library prepared by shotgun cloning. The nucleotide sequence of the mpd gene was determined. The gene could be effectively expressed in Escherichia coli.

The organochlorines (OClPs) and organophosphates (OPPs) pesticides in surface and ground water having intensive agriculture activity were investigated to evaluate their potential pollution and risks on human health. As per USEPA 8081 B method, liquid-liquid extraction followed by Gas-Chromatographic technique with electron capture detector and mass selective detector (GC-MS) were used for monit...

BACKGROUND In this investigation we documented the pesticide urinary metabolite levels of farmworker children in North Carolina, determined the number of different metabolites detected for each child, and delineated risk factors associated with the number of metabolites. METHODS Urine samples were collected from 60 Latino farmworker children 1-6 years of age (34 female, 26 male). Interviews w...

Displacement of muscarinic radioligands by the cholinesterase inhibitors parathion, paraoxon, physostigmine and phenyl saligenin cyclic phosphate was examined in rat cortex and brain stem, human cortex and brain stem, and in Chinese hamster ovary (CHO) cells expressing human M2 or M4 muscarinic acetylcholine receptors. None of the cholinesterase inhibitors tested significantly affected binding ...

We have developed a sensitive electrochemical sensor for Organophosphorus pesticide methyl parathion (MP) using silver particles supported graphene nanoribbons (Ag@GNRs). The Ag@GNRs nanocomposite was prepared through facile wet chemical strategy and characterized by TEM, EDX, XRD, Raman, UV-visible, electrochemical and impedance spectroscopies. The Ag@GNRs film modified screen printed carbon e...

Weekly composite air samples were collected from early April through to mid-September 1995 at three paired urban and agricultural sites along the Mississippi River region of the Midwestern United States. The paired sampling sites were located in Mississippi, Iowa, and Minnesota. A background site, removed from dense urban and agricultural areas, was located on the shore of Lake Superior in Mich...