نتایج جستجو برای: paternal effects
تعداد نتایج: 1551805 فیلتر نتایج به سال:
BACKGROUND The effect of paternal age on semen quality is controversial. In this retrospective study, the aim was to investigate the effects of advancing age on sperm parameters including reactive oxygen species (ROS), total antioxidant capacity (TAC) and sperm DNA damage in infertile men. We also examined whether paternal age >40 y is associated with higher risk of sperm DNA damage. METHODS ...
Breast cancer is a global public health problem and accumulating evidence indicates early-life exposures as relevant factors in the disease risk determination. Recent studies have shown that paternal nutrition can influence offspring health including breast cancer risk. Selenium is a micronutrient with essential role in central aspects of embryogenesis, male fertility and cancer and that has be...
AIM/HYPOTHESIS Maternal diabetes and high-fat feeding during pregnancy have been linked to later life outcomes in offspring. To investigate the effects of both maternal and paternal hyperglycemia on offspring phenotypes, we utilized an autosomal dominant mouse model of diabetes (hypoinsulinemic hyperglycemia in Akita mice). We determined metabolic and skeletal phenotypes in wildtype offspring o...
Previous Y-chromosome studies have demonstrated that Ashkenazi Levites, members of a paternally inherited Jewish priestly caste, display a distinctive founder event within R1a, the most prevalent Y-chromosome haplogroup in Eastern Europe. Here we report the analysis of 16 whole R1 sequences and show that a set of 19 unique nucleotide substitutions defines the Ashkenazi R1a lineage. While our su...
BACKGROUND Several studies have assessed the risks of uteroplacental bleeding disorders in relation to maternal characteristics. The association between uteroplacental bleeding disorders and paternal characteristics, however, has received considerably less attention. Data on paternal demographics, notably race and age, from birth certificate data are becoming increasingly incomplete in recent y...
Climate change is rapidly altering the thermal environment in terrestrial and aquatic systems. Transgenerational plasticity (TGP) – which occurs when temperatures experienced by parental generation prior to fertilization of gametes results a offspring reaction norms may mitigate effects climate change. Although “maternal effects” have been widely studied, relatively little known about TGP verte...
T h e term genomic imprinting has been used to refer to all cases where genes have differential expression depending on the sex of the parent from which they are inherited~-3. At least two distinct phenomena have been described as imprinting and it is important to distinguish between them. In fungus gnats (Sciaridae), gall midges (Cecidomyidae) and scale insects (Coccoidea), the paternal set of...
a r t i c l e i n f o In view of disease risk, Kong et al. (2012) demonstrated that most of the new mutations are explained by the age of the father at conception. Accordingly, paternal age effects have been found for a variety of offspring traits, from physical and mental health to intelligence. Here, we investigated whether facial attractiveness is significantly associated with paternal age. ...
This study examined abuse and trauma exposure as it predicted identity problems, affect dysregulation, and relational disturbance in 620 individuals from the general population. Multivariate analyses indicated that maternal (but not paternal) emotional abuse was uniquely associated with elevations on all 7 scales of the Inventory of Altered Self-Capacities (IASC): Interpersonal Conflicts, Ideal...
OBJECTIVE Parental alcoholism is generally found to be a strong predictor of alcohol misuse. Although the majority of siblings agree on the presence of parental alcohol issues, there is a significant minority who do not. METHOD The current study analyzed sibling data from the 1979 National Longitudinal Survey of Youth using multilevel modeling, which accounts for the nested structure of the d...
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